[HTML][HTML] Malic enzyme 1 (ME1) in the biology of cancer: it is not just intermediary metabolism

FA Simmen, I Alhallak… - Journal of molecular …, 2020 - jme.bioscientifica.com
Malic enzyme 1 (ME1) is a cytosolic protein that catalyzes the conversion of malate to
pyruvate while concomitantly generating NADPH from NADP. Early studies identified ME1 …

[HTML][HTML] The clinical and theranostic values of activated leukocyte cell adhesion molecule (ALCAM)/CD166 in human solid cancers

Y Yang, AJ Sanders, QP Dou, DG Jiang, AX Li… - Cancers, 2021 - mdpi.com
Simple Summary ALCAM (activated leukocyte cell adhesion molecule) is an important
regulator in human cancers, particularly solid tumours. Its expression in cancer tissues has …

M6A reader YTHDF1 promotes malignant progression of laryngeal squamous carcinoma through activating the EMT pathway by EIF4A3

H Guo, Q Han, X Guan, Z Li, Y Wang, L He, Y Guo… - Cellular …, 2024 - Elsevier
Laryngeal squamous cell carcinoma (LSCC) is one of the common malignant tumors in the
head and neck region, and its high migration and invasion seriously threaten the survival …

[HTML][HTML] IGF2BP2 acts as am6A modification regulator in laryngeal squamous cell carcinoma through facilitating CDK6 mRNA stabilization

X Tang, Q Tang, S Li, M Li, T Yang - Cell Death Discovery, 2023 - nature.com
Laryngeal squamous cell carcinoma (LSCC) is one of the most commonly seen cancers in
the head and neck region with increasing morbidity and mortality globally. N6 …

[HTML][HTML] NAD pool as an antitumor target against cancer stem cells in head and neck cancer

LE Navas, E Blanco-Alcaina, E Suarez-Martinez… - Journal of Experimental …, 2023 - Springer
Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group of tumors that
affect different anatomical locations. Despite this heterogeneity, HNSCC treatment depends …

[HTML][HTML] HDAC5-mediated PRAME regulates the proliferation, migration, invasion, and EMT of laryngeal squamous cell carcinoma via the PI3K/AKT/mTOR signaling …

L Yu, H Cao, JW Yang, WX Meng, C Yang, JT Wang… - Open …, 2023 - degruyter.com
Laryngeal squamous cell carcinoma (LSCC) is an aggressive and lethal malignant
neoplasm with extremely poor prognoses. Accumulating evidence has indicated that …

LncRNA-associated ceRNA network reveals novel potential biomarkers of laryngeal squamous cell carcinoma

Z Jing, S Guo, P Zhang, Z Liang - Technology in cancer …, 2020 - journals.sagepub.com
Objective: This study aims to construct a systematic mRNA-miRNA-lncRNA network to
identify novel lncRNAs and miRNAs biomarkers for laryngeal squamous cell carcinoma …

Overexpression of malic enzyme is involved in breast cancer growth and is correlated with poor prognosis

WC Hu, YF Yang, CF Cheng, YT Tu… - Journal of Cellular …, 2024 - Wiley Online Library
Malic enzyme (ME) genes are key functional metabolic enzymes playing a crucial role in
carcinogenesis. However, the detailed effects of ME gene expression on breast cancer …

[HTML][HTML] Laryngeal squamous cell carcinoma: potential molecular mechanism and prognostic signature based on immune-related genes

BY Mo, GS Li, SN Huang, ZX Wei, YS Su… - … medical journal of …, 2020 - ncbi.nlm.nih.gov
Laryngeal Squamous Cell Carcinoma: Potential Molecular Mechanism and Prognostic
Signature Based on Immune-Related Genes - PMC Back to Top Skip to main content NIH …

ALCAM is a biomarker of tumor aggressiveness and worse prognosis in glottic laryngeal squamous cell carcinoma

P Nicolau‐Neto, BC Peryassú, FN de Carvalho… - Head & …, 2024 - Wiley Online Library
Background Laryngeal squamous cell carcinoma (LSCC) is the second most frequent head
and neck tumor. Prognosis of patients with LSCC has not improved in recent decades …