Microneedle-based biosensing
Microneedles (MNs) are microscopic needles that are applied to the skin in a minimally
invasive way to facilitate transdermal drug delivery and/or uptake of interstitial fluid from the …
invasive way to facilitate transdermal drug delivery and/or uptake of interstitial fluid from the …
Contribution of the gut microbiome to drug disposition, pharmacokinetic and pharmacodynamic variability
SM Tsunoda, C Gonzales, AK Jarmusch… - Clinical …, 2021 - Springer
The trillions of microbes that make up the gut microbiome are an important contributor to
health and disease. With respect to xenobiotics, particularly orally administered compounds …
health and disease. With respect to xenobiotics, particularly orally administered compounds …
Tandem mass spectrometry molecular networking as a powerful and efficient tool for drug metabolism studies
Molecular networking (MN) has become a popular data analysis method for untargeted
mass spectrometry (MS)/MS-based metabolomics. Recently, MN has been suggested as a …
mass spectrometry (MS)/MS-based metabolomics. Recently, MN has been suggested as a …
Finger sweat analysis enables short interval metabolic biomonitoring in humans
J Brunmair, M Gotsmy, L Niederstaetter… - Nature …, 2021 - nature.com
Metabolic biomonitoring in humans is typically based on the sampling of blood, plasma or
urine. Although established in the clinical routine, these sampling procedures are often …
urine. Although established in the clinical routine, these sampling procedures are often …
Advances in microbiome-derived solutions and methodologies are founding a new era in skin health and care
A Gueniche, O Perin, A Bouslimani, L Landemaine… - Pathogens, 2022 - mdpi.com
The microbiome, as a community of microorganisms and their structural elements, genomes,
metabolites/signal molecules, has been shown to play an important role in human health …
metabolites/signal molecules, has been shown to play an important role in human health …
An overview of the latest metabolomics studies on atopic eczema with new directions for study
J Afghani, C Traidl-Hoffmann… - International Journal of …, 2022 - mdpi.com
Atopic eczema (AE) is an inflammatory skin disorder affecting approximately 20% of children
worldwide and early onset can lead to asthma and allergies. Currently, the mechanisms of …
worldwide and early onset can lead to asthma and allergies. Currently, the mechanisms of …
Transfer of antibiotics and their metabolites in human milk: Implications for infant health and microbiota
Antibiotics are an essential tool for perinatal care. While antibiotics can play a life‐saving
role for both parents and infants, they also cause collateral damage to the beneficial bacteria …
role for both parents and infants, they also cause collateral damage to the beneficial bacteria …
Connecting environmental exposure and neurodegeneration using cheminformatics and high resolution mass spectrometry: potential and challenges
Connecting chemical exposures over a lifetime to complex chronic diseases with
multifactorial causes such as neurodegenerative diseases is an immense challenge …
multifactorial causes such as neurodegenerative diseases is an immense challenge …
Tear Fluid as a Matrix for Biomonitoring Environmental and Chemical Exposures
P Amini, JO Okeme - Current environmental health reports, 2024 - Springer
Purpose Exposures to hazardous chemicals have been linked to many detrimental health
effects and it is therefore critical to have effective biomonitoring methods to better evaluate …
effects and it is therefore critical to have effective biomonitoring methods to better evaluate …
Efficient extraction of interstitial fluid using an ultrasonic-powered replaceable hexagram-shaped hydrogel microneedle patch for monitoring of dermal …
Monitoring biomarkers and pharmacokinetics is crucial for the precise diagnosis and
treatment of chronic skin diseases. Dermal interstitial fluid (ISF) presents an attractive …
treatment of chronic skin diseases. Dermal interstitial fluid (ISF) presents an attractive …