Crohn's disease

G Roda, S Chien Ng, PG Kotze, M Argollo… - Nature Reviews …, 2020 - nature.com
Crohn's disease is an inflammatory bowel disease that is characterized by chronic
inflammation of any part of the gastrointestinal tract, has a progressive and destructive …

Risk of surgery for inflammatory bowel diseases has decreased over time: a systematic review and meta-analysis of population-based studies

AD Frolkis, J Dykeman, ME Negrón, J Debruyn, N Jette… - Gastroenterology, 2013 - Elsevier
Background & Aims The inflammatory bowel diseases (IBDs) are chronic diseases that often
require surgery. However, the risk of requirement of surgery over time has not been well …

Etrolizumab as induction and maintenance therapy for ulcerative colitis in patients previously treated with tumour necrosis factor inhibitors (HICKORY): a phase 3 …

L Peyrin-Biroulet, A Hart, P Bossuyt, M Long… - The lancet …, 2022 - thelancet.com
Background Etrolizumab is a gut-targeted, anti-β7 integrin, monoclonal antibody. In an
earlier phase 2 induction study, etrolizumab significantly improved clinical remission …

The second European evidenced-based consensus on reproduction and pregnancy in inflammatory bowel disease

CJ Van der Woude, S Ardizzone… - Journal of Crohn's …, 2015 - academic.oup.com
Trying to conceive and being pregnant is an emotional period for those involved. In the
majority of patients suffering from inflammatory bowel disease, maintenance therapy is …

Etrolizumab versus adalimumab or placebo as induction therapy for moderately to severely active ulcerative colitis (HIBISCUS): two phase 3 randomised, controlled …

DT Rubin, I Dotan, A DuVall, Y Bouhnik… - The lancet …, 2022 - thelancet.com
Background Etrolizumab is a gut-targeted anti-β7 integrin monoclonal antibody. In an earlier
phase 2 induction study, etrolizumab significantly improved clinical remission relative to …

Etrolizumab versus infliximab for the treatment of moderately to severely active ulcerative colitis (GARDENIA): a randomised, double-blind, double-dummy, phase 3 …

S Danese, JF Colombel, M Lukas… - The lancet …, 2022 - thelancet.com
Background Etrolizumab is a gut-targeted anti-β7 integrin monoclonal antibody. In a
previous phase 2 induction study, etrolizumab significantly improved clinical remission …

European evidence based consensus on surgery for ulcerative colitis

T Øresland, WA Bemelman… - Journal of Crohn's …, 2015 - academic.oup.com
The goal of this consensus initiated by the European Crohn's and Colitis Organisation
(ECCO) was to establish European consensus guidelines for the surgical treatment of …

Second N-ECCO consensus statements on the European nursing roles in caring for patients with Crohn's disease or ulcerative colitis

K Kemp, L Dibley, U Chauhan… - Journal of Crohn's …, 2018 - academic.oup.com
1.1. Aim The overarching aim of ECCO is to improve the care of patients with IBD through
the development of guidelines, education and research. Current evidence is fundamental in …

Etrolizumab for maintenance therapy in patients with moderately to severely active ulcerative colitis (LAUREL): a randomised, placebo-controlled, double-blind, phase …

S Vermeire, PL Lakatos, T Ritter, S Hanauer… - The Lancet …, 2022 - thelancet.com
Background Etrolizumab is a gut-targeted anti-β7 integrin monoclonal antibody. In a
previous phase 2 induction study, etrolizumab significantly improved clinical remission …

Surgical rates for Crohn's disease are decreasing: a population-based time trend analysis and validation study

C Ma, GW Moran, EI Benchimol… - Official journal of the …, 2017 - journals.lww.com
Objectives: Temporal changes for intestinal resections for Crohn's disease (CD) are
controversial. We validated administrative database codes for CD diagnosis and surgery in …