Adipose tissue-derived stem cells in regenerative medicine

L Frese, PE Dijkman, SP Hoerstrup - Transfusion Medicine and …, 2016 - karger.com
In regenerative medicine, adult stem cells are the most promising cell types for cell-based
therapies. As a new source for multipotent stem cells, human adipose tissue has been …

Concise review: cancer cells, cancer stem cells, and mesenchymal stem cells: influence in cancer development

F Papaccio, F Paino, T Regad… - Stem cells …, 2017 - academic.oup.com
Tumors are composed of different types of cancer cells that contribute to tumor
heterogeneity. Among these populations of cells, cancer stem cells (CSCs) play an …

Adipocyte biology in breast cancer: From silent bystander to active facilitator

J Choi, YJ Cha, JS Koo - Progress in lipid research, 2018 - Elsevier
Adipocytes account for the largest proportion among the cells that comprise breast tissue;
therefore, they are considered to be a critical cell type in the tumor microenvironment of …

Concise review: Adipose-derived stromal vascular fraction cells and stem cells: let's not get lost in translation

JM Gimble, BA Bunnell, ES Chiu, F Guilak - Stem cells, 2011 - academic.oup.com
Subcutaneous fat has emerged as an alternative tissue source for stromal/stem cells in
regenerative medicine. Over the past decade, international research efforts have …

A biologic scaffold–associated type 2 immune microenvironment inhibits tumor formation and synergizes with checkpoint immunotherapy

MT Wolf, S Ganguly, TL Wang, CW Anderson… - Science translational …, 2019 - science.org
Biomaterials in regenerative medicine are designed to mimic and modulate tissue
environments to promote repair. Biologic scaffolds (derived from decellularized tissue …

MSCs derived from iPSCs with a modified protocol are tumor-tropic but have much less potential to promote tumors than bone marrow MSCs

Q Zhao, CA Gregory, RH Lee… - Proceedings of the …, 2015 - National Acad Sciences
Mesenchymal stem or stromal cells (MSCs) have many potential therapeutic applications
including therapies for cancers and tissue damages caused by cancers or radical cancer …

Human adipose tissue-derived stromal/stem cells promote migration and early metastasis of triple negative breast cancer xenografts

BG Rowan, JM Gimble, M Sheng, M Anbalagan… - PloS one, 2014 - journals.plos.org
Background Fat grafting is used to restore breast defects after surgical resection of breast
tumors. Supplementing fat grafts with adipose tissue-derived stromal/stem cells (ASCs) is …

Adipose tissue and breast epithelial cells: a dangerous dynamic duo in breast cancer

YY Wang, C Lehuédé, V Laurent, B Dirat, S Dauvillier… - Cancer letters, 2012 - Elsevier
Among the many different cell types surrounding breast cancer cells, the most abundant are
those that compose mammary adipose tissue, mainly mature adipocytes and progenitors …

[HTML][HTML] Adipose-derived Mesenchymal Stem Cells (ASCs) may favour breast cancer recurrence via HGF/c-Met signaling

V Eterno, A Zambelli, L Pavesi, L Villani, V Zanini… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Adipose tissue is a reservoir of Mesenchymal Stem Cells (Adipose-derived Mesenchymal
Stem Cells, ASCs), endowed with regenerative properties. Fat graft was proposed for breast …

Mesenchymal stem cell secretome and regenerative therapy after cancer

L Zimmerlin, TS Park, ET Zambidis, VS Donnenberg… - Biochimie, 2013 - Elsevier
Cancer treatment generally relies on tumor ablative techniques that can lead to major
functional or disfiguring defects. These post-therapy impairments require the development of …