Pharmacology of diosmin, a citrus flavone glycoside: an updated review
SH Gerges, SA Wahdan, DA Elsherbiny… - European journal of …, 2022 - Springer
Flavonoids are phytochemicals that are well known for their beneficial pharmacological
properties. Diosmin is a flavone glycoside derived from hesperidin, a flavanone abundantly …
properties. Diosmin is a flavone glycoside derived from hesperidin, a flavanone abundantly …
Ketamine induces ferroptosis of liver cancer cells by targeting lncRNA PVT1/miR-214-3p/GPX4
GN He, NR Bao, S Wang, M Xi, TH Zhang… - Drug design …, 2021 - Taylor & Francis
Background Liver cancer ranks the top four malignant cancer type worldwide, which needs
effective and safe treatment. Ferroptosis is a novel form of regulated cell death driven by iron …
effective and safe treatment. Ferroptosis is a novel form of regulated cell death driven by iron …
Multi-spectroscopic investigation, molecular docking and molecular dynamic simulation of competitive interactions between flavonoids (quercetin and rutin) and …
The main mechanism for drug-drug interaction is displacement reaction of ligands from their
protein binding sites. The aim of this study was to evaluate anticancer drug sorafenib …
protein binding sites. The aim of this study was to evaluate anticancer drug sorafenib …
Current perspective of traditional Chinese medicines and active ingredients in the therapy of hepatocellular carcinoma
Y Li, Y Li, J Zhang, L Ji, M Li, X Sun… - Journal of …, 2022 - Taylor & Francis
Hepatocellular carcinoma (HCC) is one of the leading lethal tumors worldwide, and the
treatment remains a great medical challenge. Surgery and chemotherapy are current …
treatment remains a great medical challenge. Surgery and chemotherapy are current …
[HTML][HTML] Therapeutic potential of camel milk exosomes against HepaRG cells with potent apoptotic, anti-inflammatory, and anti-angiogenesis effects for colostrum …
AM El-Kattawy, O Algezawy, MY Alfaifi… - Biomedicine & …, 2021 - Elsevier
This study aimed to evaluate and compare the therapeutic effect of camel milk exosomes
derived from colostrum, early, mid, and late lactation periods on liver cancer HepaRG cells …
derived from colostrum, early, mid, and late lactation periods on liver cancer HepaRG cells …
Self-targeting platinum (IV) amphiphilic prodrug nano-assembly as radiosensitizer for synergistic and safe chemoradiotherapy of hepatocellular carcinoma
Chemoradiotherapy is a widely used treatment for patients with malignancies such as
hepatocellular carcinoma (HCC). However, it remains challenging to realize safe and …
hepatocellular carcinoma (HCC). However, it remains challenging to realize safe and …
[HTML][HTML] Innovative challenge for the inhibition of hepatocellular carcinoma progression by combined targeting of HSP90 and STAT3/HIF-1α signaling
S Saber, EE Abd El-Fattah, AM Abdelhamid… - Biomedicine & …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is the third foremost cause of cancer-related deaths. HCC
has a very bad prognosis because it is asymptomatic in the early stages, resulting in a late …
has a very bad prognosis because it is asymptomatic in the early stages, resulting in a late …
[HTML][HTML] Ganetespib (STA-9090) augments sorafenib efficacy via necroptosis induction in hepatocellular carcinoma: Implications from preclinical data for a novel …
Sorafenib, a multikinase inhibitor, is a first-line treatment for advanced hepatocellular
carcinoma, but its long-term effectiveness is limited by the emergence of resistance …
carcinoma, but its long-term effectiveness is limited by the emergence of resistance …
Xanthosine, a purine glycoside mediates hepatic glucose homeostasis through inhibition of gluconeogenesis and activation of glycogenesis via regulating the AMPK …
Abstract Type 2 Diabetes Mellitus (T2DM) is characterized by hepatic insulin resistance,
which results in increased glucose production and reduced glycogen storage in the liver …
which results in increased glucose production and reduced glycogen storage in the liver …
[HTML][HTML] Evaluation of antioxidant and anticancer activity of crude extract and different fractions of Chlorella vulgaris axenic culture grown under various …
EA El-Fayoumy, SMM Shanab, HS Gaballa… - … Medicine and Therapies, 2021 - Springer
Background Chlorella vulgaris is a microalga potentially used for pharmaceutical, animal
feed, food supplement, aquaculture and cosmetics. The current study aims to study the …
feed, food supplement, aquaculture and cosmetics. The current study aims to study the …