Short sleep duration and health outcomes: a systematic review, meta-analysis, and meta-regression

O Itani, M Jike, N Watanabe, Y Kaneita - Sleep medicine, 2017 - Elsevier
Objective The dose–response of short sleep duration in mortality has been studied, in
addition to the incidences of notable health complications and diseases such as diabetes …

Effect of exercise on sleep quality and insomnia in middle-aged women: A systematic review and meta-analysis of randomized controlled trials

JÁ Rubio-Arias, E Marín-Cascales, DJ Ramos-Campo… - Maturitas, 2017 - Elsevier
Objective We assessed the effects of programmed exercise (PE) on sleep quality and
insomnia in middle-aged women (MAW). Methods Searches were conducted in five …

Hypnotics' association with mortality or cancer: a matched cohort study

DF Kripke, RD Langer, LE Kline - BMJ open, 2012 - bmjopen.bmj.com
Objectives An estimated 6%–10% of US adults took a hypnotic drug for poor sleep in 2010.
This study extends previous reports associating hypnotics with excess mortality. Setting A …

Effect of anxiolytic and hypnotic drug prescriptions on mortality hazards: retrospective cohort study

S Weich, HL Pearce, P Croft, S Singh, I Crome… - Bmj, 2014 - bmj.com
Objective To test the hypothesis that people taking anxiolytic and hypnotic drugs are at
increased risk of premature mortality, using primary care prescription records and after …

Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users

L Baandrup, BH Ebdrup… - Cochrane Database …, 2018 - cochranelibrary.com
Background Prolonged treatment with benzodiazepines is common practice despite clinical
recommendations of short‐term use. Benzodiazepines are used by approximately 4% of the …

Hypnotic drug risks of mortality, infection, depression, and cancer: but lack of benefit

DF Kripke - F1000Research, 2018 - pmc.ncbi.nlm.nih.gov
This is a review of hypnotic drug risks and benefits. Almost every month, new information
appears about the risks of hypnotics (sleeping pills). The most important risks of hypnotics …

Hypnotic medications and suicide: risk, mechanisms, mitigation, and the FDA

WV McCall, RM Benca, PB Rosenquist… - American journal of …, 2017 - Am Psychiatric Assoc
Objective: Insomnia is associated with increased risk for suicide. The Food and Drug
Administration (FDA) has mandated that warnings regarding suicide be included in the …

Benzodiazepines and risk of all cause mortality in adults: cohort study

E Patorno, RJ Glynn, R Levin, MP Lee, KF Huybrechts - Bmj, 2017 - bmj.com
Objectives To evaluate the risk of all cause mortality associated with initiating compared with
not initiating benzodiazepines in adults, and to address potential treatment barriers and …

Chronic insomnia: clinical and research challenges–an agenda

D Riemann, K Spiegelhalder, C Espie… - …, 2011 - thieme-connect.com
Chronic insomnia afflicts up to 10% of the population in Western industrialized countries. It is
characterized by delayed sleep onset, problems in maintaining sleep, early morning …

Association between benzodiazepines and suicide risk: a matched case-control study

V Cato, F Holländare, A Nordenskjöld, T Sellin - BMC psychiatry, 2019 - Springer
Background It is unclear whether benzodiazepines increase the risk of suicide. The aim of
this study was to test the hypothesis that benzodiazepines are associated with an increased …