New evidence on the management of Lewy body dementia

JP Taylor, IG McKeith, DJ Burn, BF Boeve… - The Lancet …, 2020 - thelancet.com
Dementia with Lewy bodies and Parkinson's disease dementia, jointly known as Lewy body
dementia, are common neurodegenerative conditions. Patients with Lewy body dementia …

Dementia with Lewy bodies: an update and outlook

TF Outeiro, DJ Koss, D Erskine, L Walker… - Molecular …, 2019 - Springer
Dementia with Lewy bodies (DLB) is an age-associated neurodegenerative disorder
producing progressive cognitive decline that interferes with normal life and daily activities …

The role of movement analysis in diagnosing and monitoring neurodegenerative conditions: Insights from gait and postural control

C Buckley, L Alcock, R McArdle, RZU Rehman… - Brain sciences, 2019 - mdpi.com
Quantifying gait and postural control adds valuable information that aids in understanding
neurological conditions where motor symptoms predominate and cause considerable …

Cognitive impairment in older adults: epidemiology, diagnosis, and treatment

NP Palmer, BT Ortega, P Joshi - Psychiatric Clinics, 2022 - psych.theclinics.com
With an increasingly aging population, health care providers will treat a higher number of
patients with cognitive impairment. Identifying cognitive impairment and intervening early …

Differentiating dementia disease subtypes with gait analysis: feasibility of wearable sensors?

R Mc Ardle, S Del Din, B Galna, A Thomas… - Gait & posture, 2020 - Elsevier
Background There are unique signatures of gait impairments in different dementia disease
subtypes, such as Alzheimer's disease (AD), dementia with Lewy bodies (DLB) and …

Structural and functional insights into α-synuclein fibril polymorphism

S Mehra, L Gadhe, R Bera, AS Sawner, SK Maji - Biomolecules, 2021 - mdpi.com
Abnormal accumulation of aggregated α-synuclein (α-Syn) is seen in a variety of
neurodegenerative diseases, including Parkinson's disease (PD), multiple system atrophy …

From menopause to neurodegeneration—molecular basis and potential therapy

YJ Cheng, CH Lin, HY Lane - International journal of molecular sciences, 2021 - mdpi.com
The impacts of menopause on neurodegenerative diseases, especially the changes in
steroid hormones, have been well described in cell models, animal models, and humans …

Survival time and differences between dementia with Lewy bodies and Alzheimer's disease following diagnosis: A meta-analysis of longitudinal studies

C Mueller, P Soysal, A Rongve, AT Isik… - Ageing research …, 2019 - Elsevier
Objective To synthesize the evidence across longitudinal studies comparing survival in
dementia with Lewy bodies (DLB) and Alzheimer's disease (AD). Methods We conducted a …

Sex differences in dementia with Lewy bodies: focused review of available evidence and future directions

SY Chiu, KA Wyman-Chick, TJ Ferman… - Parkinsonism & related …, 2023 - Elsevier
In this review, we summarize the current knowledge on sex differences in dementia with
Lewy bodies (DLB) relating to epidemiology, clinical features, neuropathology, biomarkers …

AI-based differential diagnosis of dementia etiologies on multimodal data

C Xue, SS Kowshik, D Lteif, S Puducheri… - Nature Medicine, 2024 - nature.com
Differential diagnosis of dementia remains a challenge in neurology due to symptom overlap
across etiologies, yet it is crucial for formulating early, personalized management strategies …