Inflammation and tumor progression: signaling pathways and targeted intervention
H Zhao, L Wu, G Yan, Y Chen, M Zhou… - Signal transduction and …, 2021 - nature.com
Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …
either promotes or suppresses tumor progression, potentially displaying opposing effects on …
Roles of tumor-associated macrophages in anti-PD-1/PD-L1 immunotherapy for solid cancers
H Zhang, L Liu, J Liu, P Dang, S Hu, W Yuan, Z Sun… - Molecular Cancer, 2023 - Springer
In recent years, tumor immunotherapy has made significant progress. However, tumor
immunotherapy, particularly immune checkpoint inhibitors (eg, PD-1/PD-L1 inhibitors) …
immunotherapy, particularly immune checkpoint inhibitors (eg, PD-1/PD-L1 inhibitors) …
CAR-T cell therapy in hematological malignancies: current opportunities and challenges
X Zhang, L Zhu, H Zhang, S Chen, Y Xiao - Frontiers in immunology, 2022 - frontiersin.org
Chimeric antigen receptor T (CAR-T) cell therapy represents a major breakthrough in cancer
treatment, and it has achieved unprecedented success in hematological malignancies …
treatment, and it has achieved unprecedented success in hematological malignancies …
Biomedical polymers: synthesis, properties, and applications
Biomedical polymers have been extensively developed for promising applications in a lot of
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …
Role of tumor microenvironment in cancer progression and therapeutic strategy
Q Wang, X Shao, Y Zhang, M Zhu, FXC Wang… - Cancer …, 2023 - Wiley Online Library
Cancer is now considered a tumor microenvironment (TME) disease, although it was
originally thought to be a cell and gene expression disorder. Over the past 20 years …
originally thought to be a cell and gene expression disorder. Over the past 20 years …
Interferons α and β in cancer: therapeutic opportunities from new insights
EC Borden - Nature Reviews Drug Discovery, 2019 - nature.com
Over the past decade, preclinical and clinical research have confirmed the essential role of
interferons for effective host immunological responses to malignant cells. Type I interferons …
interferons for effective host immunological responses to malignant cells. Type I interferons …
CAR-T cell therapy in multiple myeloma: Current limitations and potential strategies
X Zhang, H Zhang, H Lan, J Wu, Y Xiao - Frontiers in immunology, 2023 - frontiersin.org
Over the last decade, the survival outcome of patients with multiple myeloma (MM) has been
substantially improved with the emergence of novel therapeutic agents, such as proteasome …
substantially improved with the emergence of novel therapeutic agents, such as proteasome …
Primary and acquired resistance to immune checkpoint inhibitors in metastatic melanoma
Immune checkpoint inhibitors have revolutionized the treatment of patients with advanced-
stage metastatic melanoma, as well as patients with many other solid cancers, yielding long …
stage metastatic melanoma, as well as patients with many other solid cancers, yielding long …
Biological characteristics and clinical significance of soluble PD-1/PD-L1 and exosomal PD-L1 in cancer
M Niu, Y Liu, M Yi, D Jiao, K Wu - Frontiers in Immunology, 2022 - frontiersin.org
The immune checkpoint pathway consisting of the cell membrane-bound molecule
programmed death protein 1 (PD-1) and its ligand PD-L1 has been found to mediate …
programmed death protein 1 (PD-1) and its ligand PD-L1 has been found to mediate …
Local biomaterials-assisted cancer immunotherapy to trigger systemic antitumor responses
Cancer immunotherapy by educating or stimulating patients' own immune systems to attack
cancer cells has demonstrated promising therapeutic responses in the clinic. However …
cancer cells has demonstrated promising therapeutic responses in the clinic. However …