The prognosis of patients with glioblastoma (GBM) remains poor, and the use of
hyperfractionation or dose escalation beyond 60 Gy has not conferred any survival benefit …

Glioblastoma is the most common primary brain tumor in adults. Standard therapy depends
on patient age and performance status but principally involves surgical resection followed by …

Stereotactic radiosurgery (SRS), typically administered in a single session, is widely
employed to safely, efficiently, and effectively treat small intracranial lesions. However, for …

We have previously developed a multigene expression model of tumor radiosensitivity (RSI)
with clinical validation in multiple cohorts and disease sites. We hypothesized RSI would …

PURPOSE: Volumetric modulated arc therapy (VMAT), the predecessor to Varian's
RapidArc, is a novel extension of intensity-modulated radiotherapy (IMRT) wherein the dose …

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Central Nervous
System (CNS) Cancers provide interdisciplinary recommendations for managing adult CNS …

Purpose: Bevacizumab is associated with decreased vascular permeability that allows for
more aggressive radiotherapy schedules. We conducted a phase II trial in newly diagnosed …

Background and Purpose: To quantitatively compare the recurrence patterns of glioblastoma
(isocitrate dehydrogenase-wild type) versus grade 4 isocitrate dehydrogenase-mutant …

Background and purpose: Intensity-modulated radiation therapy (IMRT) could represent a
new tool to improve the therapeutic ratio in the treatment of glioblastoma. This systematic …

Background. The current standard of care of glioblastoma, the most common primary brain
tumor in adults, has remained unchanged for over a decade. Nevertheless, some …