Ethnopharmacological relevance Rheumatoid arthritis (RA) is a chronic inflammatory
autoimmune disease influenced by diverse endogenous and exogenous factors. It is …

Resveratrol is the most well-known polyphenolic stilbenoid, present in grapes, mulberries,
peanuts, rhubarb, and in several other plants. Resveratrol can play a beneficial role in the …

Inflammation is an integral part of autoimmune diseases, which are caused by dysregulation
of the immune system. This dysregulation involves an imbalance between pro-inflammatory …

The use of polyphenols as adjuvants in lowering risk factors for various debilitating diseases
has been investigated in recent years due to their possible antioxidant action. Polyphenols …

Flavonoids are natural polyphenolic compounds which are included in a panoply of drugs
and used to treat and/or manage human ailments such as metabolic, cardiovascular …

Abstract The interleukin-17 (IL-17) family comprises six members (IL-17A–17F), and
recently, all of its related receptors have been discovered. IL-17 was first discovered …

Lung cancer is a leading cause of cancer-related deaths worldwide. Lung cancer risk
factors, including smoking and exposure to environmental carcinogens, have been linked to …

ABSTRACT Introduction: The IL-23/IL-17 axis is currently considered to be crucial in the
pathogenesis of psoriasis. Human IL-23 is primarily produced by antigen-presenting cells …

Quercetin (QU) has been shown obvious anti-arthritic property in pre-clinical studies or
clinical studies. Howbeit, the underlying mechanism of it is still not revealed distinctly and …

Celastrol is a bioactive compound derived from traditional Chinese medicinal herbs of the
Celastraceae family. Celastrol is known to possess anti-inflammatory and anti-oxidant …