The formation of stable cell–cell adhesions by type I cadherins depends on the association
of their cytoplasmic domain with β-catenin, and of β-catenin with α-catenin. The binding of β …

Armadillo (ARM)-repeat proteins form a large family with diverse and fundamental functions
in many eukaryotes. ARM-repeat proteins have largely been characterised in multicellular …

Intercellular anchoring junctions are highly specialized regions of the plasma membrane
where members of the cadherin family of transmembrane adhesion molecules on opposing …

In addition to the classical neurotransmitters, acetylcholine and noradrenaline, a wide
number of peptides with neurotransmitter activity have been identified in the past few years …

The human oncogene β-catenin is a bifunctional protein with critical roles in both cell
adhesion and transcriptional regulation in the Wnt pathway,,. Wnt/β-catenin signalling has …

In recent years, a handful of model systems from the basal metazoan phylum Cnidaria have
emerged to challenge long‐held views on the evolution of animal complexity. The most …

Little is known about the molecular mechanisms responsible for axis establishment during
non-embryonic processes such as regeneration and homeostasis. To address this issue, we …

Despite long-standing interest, the molecular mechanisms underlying the establishment of
anterior–posterior (AP) polarity remain among the unsolved mysteries in metazoans. In the …

After two decades of stardom, one would think that β‐catenin has revealed all of its most
intimate details. Yet the essence of its duality has remained mysterious—how can a single …

A large dinoflagellate bloom in Walker Bay (South Africa) in January 2017 impacted 3 land-
based abalone farms resulting in the death of several million animals. Satellite-derived …