This review provides a broad overview of the state of research in the genetics of anxiety
disorders (AD). Genetic epidemiological studies report a moderate level of familial …

Abstract Purpose: COVID-19, a novel infection, presented with several complications,
including socioeconomical and reproductive health challenges such as erectile dysfunction …

Abstract Data from the Genetic Association Information Network (GAIN) genome-wide
association study (GWAS) in major depressive disorder (MDD) were used to explore …

Context Inflammation is increasingly recognized as contributing to the pathogenesis of major
depressive disorder (MDD), even in individuals who are otherwise medically healthy. Most …

This comprehensive review article embarks on an extensive exploration of anxiety research,
navigating a multifaceted landscape that incorporates various disciplines, such as molecular …

BackgroundWe sought to ascertain the strength of evidence for association between the 5-
HTTLPR polymorphism and unipolar depression. MethodWe applied meta-analytic …

Here we present a strategy to determine the genetic basis of variance in complex
phenotypes that arise from natural, as opposed to induced, genetic variation in mice. We …

A problem of 'missing heritability'has been identified following recent genome-wide
association (GWA) studies of single nucleotide polymorphisms (SNPs) associated with …

Background Disrupted serotonergic signaling is often a feature of depression and the role of
the serotonin transporter gene (SLC6A4), responsible for serotonin re-uptake, has received …

Variation in personality traits is 30–60% attributed to genetic influences. Attempts to unravel
these genetic influences at the molecular level have, so far, been inconclusive. We …