MicroRNAs (miRNAs) are short non-coding RNAs that inhibit the expression of target genes
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …

MicroRNAs (miRNAs) are∼ 22 nt RNAs that direct posttranscriptional repression of mRNA
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …

MicroRNAs (miRNAs) are short, regulatory RNAs that act as post-transcriptional repressors
of gene expression in diverse biological contexts. The emergence of small RNA-mediated …

Gene expression profiling by high-throughput sequencing reveals qualitative and
quantitative changes in RNA species at steady state but obscures the intracellular dynamics …

Argonaute-bound microRNAs silence mRNA expression in a dynamic and regulated
manner to control organismal development, physiology, and disease. We employed …

RNA tailing, or the addition of non-templated nucleotides to the 3′ end of RNA, is the most
frequent and conserved type of RNA modification. The addition of tails and their composition …

MicroRNAs (miRNAs) are major post‐transcriptional regulators of gene expression. They
base pair with the complementary target mRNA at the 3′ UTR and modulate cellular …

The transcription factor Pax5 controls B cell development, but its role in mature B cells is
largely enigmatic. Here, we demonstrated that the loss of Pax5 by conditional mutagenesis …

MicroRNAs (miRNAs) associated with Argonaute proteins (AGOs) regulate gene expression
in mammals. miRNA 3'ends are subject to frequent sequence modifications, which have …

TENTs generate miRNA isoforms by 3'tailing. However, little is known about how tailing
regulates miRNA function. Here, we generate isogenic HEK293T cell lines in which TENT2 …