Techniques of assessing small airways dysfunction
W McNulty, OS Usmani - European clinical respiratory journal, 2014 - Taylor & Francis
The small airways are defined as those less than 2 mm in diameter. They are a major site of
pathology in many lung diseases, not least chronic obstructive pulmonary disease (COPD) …
pathology in many lung diseases, not least chronic obstructive pulmonary disease (COPD) …
Small airway obstruction in COPD: new insights based on micro-CT imaging and MRI imaging
JC Hogg, JE McDonough, M Suzuki - Chest, 2013 - Elsevier
The increase in total cross-sectional area in the distal airways of the human lung enhances
the mixing of each tidal breath with end-expiratory gas volume by slowing bulk flow and …
the mixing of each tidal breath with end-expiratory gas volume by slowing bulk flow and …
Expanding applications of pulmonary MRI in the clinical evaluation of lung disorders: Fleischner Society position paper
H Hatabu, Y Ohno, WB Gefter, G Parraga, B Madore… - Radiology, 2020 - pubs.rsna.org
Pulmonary MRI provides structural and quantitative functional images of the lungs without
ionizing radiation, but it has had limited clinical use due to low signal intensity from the lung …
ionizing radiation, but it has had limited clinical use due to low signal intensity from the lung …
Hyperpolarized 3He and 129Xe MR Imaging in Healthy Volunteers and Patients with Chronic Obstructive Pulmonary Disease
Purpose To quantitatively compare hyperpolarized helium 3 (3He) and xenon 129 (129Xe)
magnetic resonance (MR) images obtained within 5 minutes in healthy volunteers and …
magnetic resonance (MR) images obtained within 5 minutes in healthy volunteers and …
Hyperpolarized 3He and 129Xe MRI: Differences in asthma before bronchodilation
S Svenningsen, M Kirby, D Starr… - Journal of magnetic …, 2013 - Wiley Online Library
Purpose To compare hyperpolarized helium‐3 (3He) and xenon‐129 (129Xe) MRI in
asthmatics before and after salbutamol inhalation. Materials and Methods Seven asthmatics …
asthmatics before and after salbutamol inhalation. Materials and Methods Seven asthmatics …
Hyperpolarized gas MR imaging: technique and applications
JE Roos, HP McAdams, SS Kaushik… - Magnetic Resonance …, 2015 - mri.theclinics.com
Lung diseases affect the conducting airways, the gas exchange parenchyma, or both. As a
result, they have a high impact on patients' morbidity, and quality of life. Chronic obstructive …
result, they have a high impact on patients' morbidity, and quality of life. Chronic obstructive …
Lung MRI with hyperpolarised gases: current & future clinical perspectives
The use of pulmonary MRI in a clinical setting has historically been limited. Whilst CT
remains the gold-standard for structural lung imaging in many clinical indications, technical …
remains the gold-standard for structural lung imaging in many clinical indications, technical …
The fissure: interlobar collateral ventilation and implications for endoscopic therapy in emphysema
TD Koster, DJ Slebos - International journal of chronic obstructive …, 2016 - Taylor & Francis
In patients with severe emphysema, bronchoscopic lung volume reduction using one-way
valves is a promising therapeutic option to improve lung function and quality of life. The goal …
valves is a promising therapeutic option to improve lung function and quality of life. The goal …
What are ventilation defects in asthma?
Background Hyperpolarised 3He MRI provides a way to visualise regional pulmonary
functional abnormalities that in asthma are thought to be related to airway morphological …
functional abnormalities that in asthma are thought to be related to airway morphological …
Hyperpolarized 3He Ventilation Defects Used to Predict Pulmonary Exacerbations in Mild to Moderate Chronic Obstructive Pulmonary Disease
Purpose To evaluate the predictive value of imaging and clinical and physiological
measurements of chronic obstructive pulmonary disease (COPD chronic obstructive …
measurements of chronic obstructive pulmonary disease (COPD chronic obstructive …