Review of β‐carboline and its derivatives as selective MAO‐A inhibitors

F Benny, S Kumar, J Jayan… - Archiv der …, 2023 - Wiley Online Library
As flavin adenine dinucleotide (FAD)‐dependent enzymes, monoamine oxidases (MAOs)
catalyze the oxidative deamination of various endogenous and exogenous amines. MAO‐A …

SSAO/VAP-1 in cerebrovascular disorders: A potential therapeutic target for stroke and Alzheimer's disease

M Unzeta, M Hernàndez-Guillamon, P Sun… - International journal of …, 2021 - mdpi.com
The semicarbazide-sensitive amine oxidase (SSAO), also known as vascular adhesion
protein-1 (VAP-1) or primary amine oxidase (PrAO), is a deaminating enzyme highly …

Role of semicarbazide-sensitive amine oxidase on glucose transport and GLUT4 recruitment to the cell surface in adipose cells

G Enrique-Tarancón, L Marti, N Morin… - Journal of Biological …, 1998 - ASBMB
The previous characterization of an abundant population of non-adrenergic imidazoline-I 2
binding sites in adipocytes and the recent demonstration of the interplay between these …

Substrates of semicarbazide-sensitive amine oxidase co-operate with vanadate to stimulate tyrosine phosphorylation of insulin-receptor-substrate proteins …

G ENRIQUE-TARANCÓN, I CASTAN… - Biochemical …, 2000 - portlandpress.com
It has been shown that the combination of benzylamine or tyramine and low concentrations
of vanadate markedly stimulates glucose transport in rat adipocytes by a mechanism that …

Semicarbazide-sensitive amine oxidase activity exerts insulin-like effects on glucose metabolism and insulin-signaling pathways in adipose cells

A Zorzano, A Abella, L Marti, C Carpéné… - … et Biophysica Acta (BBA …, 2003 - Elsevier
Semicarbazide-sensitive amine oxidase (SSAO) is very abundant at the plasma membrane
in adipocytes. The combination of SSAO substrates and low concentrations of vanadate …

Tissue activity and cellular localization of human semicarbazide-sensitive amine oxidase

N Andrés, JM Lizcano, MJ Rodríguez… - … of Histochemistry & …, 2001 - journals.sagepub.com
Semicarbazide-sensitive amine oxidase (SSAO), widely distributed in highly vascularized
mammalian tissues, metabolizes endogenous and xenobiotic aromatic and aliphatic …

Dopamine in human follicular fluid is associated with cellular uptake and metabolism-dependent generation of reactive oxygen species in granulosa cells: implications …

S Saller, L Kunz, D Berg, U Berg, H Lara… - Human …, 2014 - academic.oup.com
STUDY QUESTION Is the neurotransmitter dopamine (DA) in the human ovary involved in
the generation of reactive oxygen species (ROS)? SUMMARY ANSWER Human ovarian …

[HTML][HTML] Protective effects of the novel amine-oxidase inhibitor multi-target drug SZV 1287 on streptozotocin-induced beta cell damage and diabetic complications in …

V Tékus, ÁI Horváth, K Szabadfi… - Biomedicine & …, 2021 - Elsevier
Diabetes mellitus is a common metabolic disease leading to hyperglycemia due to
insufficient pancreatic insulin production or effect. Amine oxidase copper containing 3 …

Purification and characterization of membrane-bound semicarbazide-sensitive amine oxidase (SSAO) from bovine lung

JM Lizcano, KF Tipton, M Unzeta - Biochemical Journal, 1998 - portlandpress.com
Semicarbazide-sensitive amine oxidase (SSAO) has been purified from bovine lung
microsomes in a form which is catalytically active and stable to storage. The enzyme, an …

Inhibition of bovine lung semicarbazide-sensitive amine oxidase (SSAO) by some hydrazine derivatives

JM Lizcano, AF De Arriba, KF Tipton… - Biochemical pharmacology, 1996 - Elsevier
Microsomal semicarbazide-sensitive amine oxidase (SSAO) from bovine lung was shown to
be inhibited by a number of hydrazine derivatives, but the mechanisms of inhibition were …