Hypoxia and mitochondrial dysfunction in pregnancy complications
Hypoxia is a common and severe stress to an organism's homeostatic mechanisms, and
hypoxia during gestation is associated with significantly increased incidence of maternal …
hypoxia during gestation is associated with significantly increased incidence of maternal …
Preeclampsia among African American pregnant women: an update on prevalence, complications, etiology, and biomarkers
M Zhang, P Wan, K Ng, K Singh… - Obstetrical & …, 2020 - journals.lww.com
Preeclampsia Among African American Pregnant Women: An Updat... : Obstetrical &
Gynecological Survey Preeclampsia Among African American Pregnant Women: An Update …
Gynecological Survey Preeclampsia Among African American Pregnant Women: An Update …
Mitochondrial dysfunction in the pathogenesis of preeclampsia
Abstract Purpose of Review Preeclampsia complicates 5–10% of all pregnancies and is a
leading cause of maternal and perinatal mortality and morbidity. The placenta plays a pivotal …
leading cause of maternal and perinatal mortality and morbidity. The placenta plays a pivotal …
Trophoblast mitochondrial function is impaired in preeclampsia and correlates negatively with the expression of soluble fms-like tyrosine kinase 1
ZK Zsengellér, A Rajakumar, JT Hunter… - … An International Journal …, 2016 - Elsevier
Preeclampsia is a common medical complication of pregnancy that is associated with
significant morbidity and mortality to the mother and the baby. Extensive human …
significant morbidity and mortality to the mother and the baby. Extensive human …
Differences and similarities in the transcriptional profile of peripheral whole blood in early and late-onset preeclampsia: insights into the molecular basis of the …
Objective: Preeclampsia (PE) can be sub-divided into early-and late-onset phenotypes. The
pathogenesis of these two phenotypes has not been elucidated. To gain insight into the …
pathogenesis of these two phenotypes has not been elucidated. To gain insight into the …
Genetic factors in the etiology of preeclampsia/eclampsia
K Ward, RN Taylor - Chesley's hypertensive disorders in pregnancy, 2015 - Elsevier
Preeclampsia is a complex familial disorder, which likely involves multiple genes in multiple
biological pathways. Family reports, twin studies, segregation analyses, linkage analyses …
biological pathways. Family reports, twin studies, segregation analyses, linkage analyses …
Downregulation of mitofusin 2 in placenta is related to preeclampsia
J Yu, X Guo, R Chen, L Feng - BioMed research international, 2016 - Wiley Online Library
Background. Mitofusin 2 (Mfn2) is a novel mitochondrial protein that is implicated in cellular
proliferation and metabolism; however, the role of Mfn2 in preeclampsia (PE) remains …
proliferation and metabolism; however, the role of Mfn2 in preeclampsia (PE) remains …
A scoping review of risk factors of hypertensive disorders of pregnancy in Black women living in high-income countries: an intersectional approach
D Baiden, K Nerenberg, EM Hillan… - Journal of …, 2024 - journals.lww.com
Background Hypertensive disorders of pregnancy (HDP) are maternity-related increases in
blood pressure (eg, gestational hypertension, preeclampsia, and eclampsia). Compared …
blood pressure (eg, gestational hypertension, preeclampsia, and eclampsia). Compared …
Testosterone decreases placental mitochondrial content and cellular bioenergetics
Placental mitochondrial dysfunction plays a central role in the pathogenesis of
preeclampsia. Since preeclampsia is a hyperandrogenic state, we hypothesized that …
preeclampsia. Since preeclampsia is a hyperandrogenic state, we hypothesized that …
Exploring the molecular aetiology of preeclampsia by massive parallel sequencing of DNA
Abstract Purpose of Review This manuscript aims to review (for the first time) studies
describing NGS sequencing of preeclampsia (PE) women's DNA. Recent Findings …
describing NGS sequencing of preeclampsia (PE) women's DNA. Recent Findings …