CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane
bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated …

The CD83 molecule has been identified to be expressed on numerous activated immune
cells, including B and T lymphocytes, monocytes, dendritic cells, microglia, and neutrophils …

Dendritic cells (DCs) are crucial to balance protective immunity and autoimmune
inflammatory processes. Expression of CD83 is a well-established marker for mature DCs …

There are many unanswered questions surrounding the function of immune cells and how
they interact with the reproductive system to support successful pregnancy or contribute to …

A well-balanced maternal immune system is crucial to maintain fetal tolerance in case of
infections during pregnancy. Immune adaptations include an increased secretion of soluble …

Pregnancy success depends greatly on a balanced immune homeostasis. The detection of
bacterial components in the upper reproductive tract in non-pregnant and pregnant women …

Preeclampsia (PE) is a complex disease of pregnancy, and an important cause of this
disease is insufficient trophoblast invasion and migration. However, the underlying …

The mechanism of generation of regulatory T cells (Treg) remains incompletely understood.
Recent studies show that CD83 has immune regulatory functions. This study aims to …

Strategically located in mucosal barriers, innate lymphoid cells (ILCs) are relevant in local
containment and tolerance of commensal microflora. ILCs have been recently described at …

A favorable outcome of pregnancy depends greatly on an adequate balance of immune
protection and fetal tolerance at the fetomaternal interface. IL-21 is a pro-inflammatory …