Gene expression occurs in two essential steps: transcription and translation. In bacteria, the
two processes are tightly coupled in time and space, and highly regulated. Tight regulation …

Bacteria live in habitats of frequently changing conditions and have evolved very
sophisticated responses to adapt to environmental changes. These responses most …

Stringent starvation protein A (SspA) is an RNA polymerase (RNAP)-associated protein
involved in nucleotide metabolism, acid tolerance and virulence of bacteria. Despite …

ABSTRACT The KorB and TrbA proteins of broad-host-range plasmid RK2 are key
regulators of the plasmid genes required for conjugative transfer. trbBp is the primary …

We have determined the solution structure of a complex containing the K50 class
homeodomain Pituitary homeobox protein 2 (PITX2) bound to its consensus DNA site …

The Escherichia coli transcriptional regulator MarA affects functions that include antibiotic
resistance, persistence, and survival. MarA functions as an activator or repressor of …

A specific interaction between the α subunit of RNA polymerase and an A+ T-rich upstream
sequence (UP element) stimulates transcription at some promoters in Escherichia coli. We …

The ability to utilize Escherichia coli as a heterologous system in which to study the
regulation of Agrobacterium tumefaciens virulence genes and the mechanism of transfer …

Protein p6 is a nonspecific DNA-binding protein occurring in high abundance in phage φ29-
infected cells. Here, we demonstrate a novel role for this versatile histone-like protein: its …

Bacteriophage φ29 gene expression takes place from four major promoters, three of them
(A2b, A2c and A3) clustered within 219 bp at a central region of the genome. Transcription …