The role of artificial intelligence and convolutional neural networks in the management of melanoma: a clinical, pathological, and radiological perspective
J Yee, C Rosendahl, LG Aoude - Melanoma Research, 2024 - journals.lww.com
Clinical dermatoscopy and pathological slide assessment are essential in the diagnosis and
management of patients with cutaneous melanoma. For those presenting with stage IIC …
management of patients with cutaneous melanoma. For those presenting with stage IIC …
Prognostic and predictive biomarkers in melanoma
Biomarkers help to inform the clinical management of patients with melanoma. For patients
with clinically localised primary melanoma, biomarkers can help to predict post-surgical …
with clinically localised primary melanoma, biomarkers can help to predict post-surgical …
[HTML][HTML] Immune subtyping of melanoma whole slide images using multiple instance learning
Determining early-stage prognostic markers and stratifying patients for effective treatment
are two key challenges for improving outcomes for melanoma patients. Previous studies …
are two key challenges for improving outcomes for melanoma patients. Previous studies …
Nomograms based on the lymphocyte–albumin–neutrophil ratio (LANR) for predicting the prognosis of nasopharyngeal carcinoma patients after definitive …
S Zhang, Z Chen, J Ling, Y Feng, Y Xie, X Liu, C Hu… - Scientific Reports, 2024 - nature.com
Much evidence has accumulated to show that inflammation and nutritional status are
associated with the prognosis of patients with various cancers. The present study was …
associated with the prognosis of patients with various cancers. The present study was …
[HTML][HTML] Baseline tumor-infiltrating lymphocyte patterns and response to immune checkpoint inhibition in metastatic cutaneous melanoma
IAJ van Duin, M Schuiveling, LS Ter Maat… - European Journal of …, 2024 - Elsevier
Introduction The presence of tumor-infiltrating lymphocytes (TILs) in melanoma has been
linked to survival. Their predictive capability for immune checkpoint inhibition (ICI) response …
linked to survival. Their predictive capability for immune checkpoint inhibition (ICI) response …
A multi-task deep learning model based on comprehensive feature integration and self-attention mechanism for predicting response to anti-PD1/PD-L1
R Wang, Q Liu, W You, Y Chen - International Immunopharmacology, 2024 - Elsevier
Background Immune checkpoint inhibitor (ICI) has been widely used in the treatment of
advanced cancers, but predicting their efficacy remains challenging. Traditional biomarkers …
advanced cancers, but predicting their efficacy remains challenging. Traditional biomarkers …
[HTML][HTML] Ecto-NOX Disulfide-Thiol Exchanger 2 (ENOX2/tNOX) Is a Potential Prognostic Marker in Primary Malignant Melanoma and May Serve as a Therapeutic …
M Böcker, E Chatziioannou, H Niessner, C Hirn… - International Journal of …, 2024 - mdpi.com
With an increasing incidence of malignant melanoma, new prognostic biomarkers for clinical
decision making have become more important. In this study, we evaluated the role of ecto …
decision making have become more important. In this study, we evaluated the role of ecto …
Artificial intelligence biomarkers for digital oncology: a case study of tumor-infiltrating lymphocytes in melanoma
R Salgado, K AbdulJabbar - Ebiomedicine, 2023 - thelancet.com
Melanoma is an immunogenic tumor that exhibits various cell types in its microenvironment,
including fibroblasts, endothelial cells, and immune cells. The interaction of tumor cells with …
including fibroblasts, endothelial cells, and immune cells. The interaction of tumor cells with …
Role of Tumor-Infiltrating Lymphocytes in Melanoma Prognosis and Treatment Strategies: A Systematic Review and Meta-Analysis
M Garutti, R Bruno, J Polesel, MA Pizzichetta, F Puglisi - Heliyon, 2024 - cell.com
Purpose Numerous studies underscore the relevance of tumor-infiltrating-lymphocytes (TILs)
as important prognostic factors for melanoma. This meta-analysis aims to provide a …
as important prognostic factors for melanoma. This meta-analysis aims to provide a …
Exploring the In Vitro and In Vivo Therapeutic Potential of BRAF and MEK Inhibitor Combination in NRAS-Mutated Melanoma
H Niessner, A Hüsch, C Kosnopfel, M Meinhardt… - Cancers, 2023 - mdpi.com
Simple Summary This study explores the therapeutic effect of the combination of BRAF and
MEK inhibitors (BRAFi+ MEKi) on NRAS-mutated melanomas in vitro, in preclinical in vivo …
MEK inhibitors (BRAFi+ MEKi) on NRAS-mutated melanomas in vitro, in preclinical in vivo …