Optimal dosing of levetiracetam for seizure prophylaxis in critically ill patients: A prospective observational study

E Valdes, T Fang, M Boffa, JA Frontera - Critical Care Medicine, 2024 - journals.lww.com
OBJECTIVES: Critically ill patients eliminate levetiracetam (LEV) more rapidly than healthy
controls, yet low doses are commonly used for seizure prophylaxis in the ICU setting. We …

Guidelines for Seizure Prophylaxis in Adults Hospitalized with Moderate–Severe Traumatic Brain Injury: A Clinical Practice Guideline for Health Care Professionals …

JA Frontera, EJ Gilmore, EL Johnson, DW Olson… - Neurocritical care, 2024 - Springer
Background There is practice heterogeneity in the use, type, and duration of prophylactic
antiseizure medications (ASMs) in patients with moderate–severe traumatic brain injury …

Levetiracetam Dosing Based on Glasgow Coma Scale Scores in Pediatric Traumatic Brain Injury Patients

V Miklus, L Trout, K Even - Neuropediatrics, 2024 - thieme-connect.com
Introduction Severe traumatic brain injury (TBI) increases the risk of early posttraumatic
seizures (EPTS). Guidelines suggest the use of prophylactic antiseizure agents, including …

Levetiracetam as an Alternative to Phenytoin for Prophylactic Use in Post-Traumatic Seizures: a Literature Review

G Nagatri, DA Situmorang, N Ramoti… - Jurnal Neuroanestesi …, 2024 - inasnacc.org
Traumatic brain injury (TBI) is a common concern for the causes of disability and mortality
and it can cause post-traumatic seizure (PTS). Currently, Brain Trauma Foundation (BTF) …

[引用][C] Levetiracetam pharmacokinetics and brain uptake in a lateral fluid percussion injury rat model

LD Coles, PG Saletti, CP Lisgaras… - … of Pharmacology and …, 2023 - ASPET