Hepadnaviral lymphotropism and its relevance to HBV persistence and pathogenesis
CS Coffin, PM Mulrooney-Cousins… - Frontiers in …, 2021 - frontiersin.org
Since the discovery of hepatitis B virus (HBV) over five decades ago, there have been many
independent studies showing presence of HBV genomes in cells of the immune system …
independent studies showing presence of HBV genomes in cells of the immune system …
Impact of hepatitis B virus genetic variation, integration, and lymphotropism in antiviral treatment and oncogenesis
Chronic Hepatitis B Virus (HBV) infection poses a significant global health burden. Although,
effective treatment and vaccinations against HBV are available, challenges still exist …
effective treatment and vaccinations against HBV are available, challenges still exist …
Porcine circovirus 2 (PCV2) population study in experimentally infected pigs developing PCV2-systemic disease or a subclinical infection
F Correa-Fiz, G Franzo, A Llorens, E Huerta, M Sibila… - Scientific reports, 2020 - nature.com
Abstract Porcine circovirus 2 (PCV2) is a single stranded DNA virus with one of the highest
mutation rates among DNA viruses. This ability allows it to generate a cloud of mutants …
mutation rates among DNA viruses. This ability allows it to generate a cloud of mutants …
Hepatitis B virus adaptation to the CD8+ T cell response: consequences for host and pathogen
Chronic viral hepatitis infections are a major public health concern, with an estimated 290
million individuals infected with hepatitis B virus (HBV) globally. This virus has been a …
million individuals infected with hepatitis B virus (HBV) globally. This virus has been a …
Characterization of full-length genomes of hepatitis B virus quasispecies in sera of patients at different phases of infection
ZT Yang, SY Huang, L Chen, F Liu… - Journal of Clinical …, 2015 - Am Soc Microbiol
Hepatitis B virus (HBV) infection results in different clinical presentation due to different
levels of immune response. Our study aimed to characterize HBV full-length genome …
levels of immune response. Our study aimed to characterize HBV full-length genome …
Machine-learning based patient classification using Hepatitis B virus full-length genome quasispecies from Asian and European cohorts
AJ Mueller-Breckenridge, F Garcia-Alcalde… - Scientific Reports, 2019 - nature.com
Chronic infection with Hepatitis B virus (HBV) is a major risk factor for the development of
advanced liver disease including fibrosis, cirrhosis, and hepatocellular carcinoma (HCC) …
advanced liver disease including fibrosis, cirrhosis, and hepatocellular carcinoma (HCC) …
The burden of hepatitis B virus (HBV) infection, genotypes and drug resistance mutations in human immunodeficiency virus-positive patients in Northwest Ethiopia
T Deressa, D Damtie, K Fonseca, S Gao, E Abate… - PLoS …, 2017 - journals.plos.org
Background In sub-Saharan Africa, the hepatitis B virus (HBV) and human
immunodeficiency virus (HIV) infections are endemic. Although there has been great …
immunodeficiency virus (HIV) infections are endemic. Although there has been great …
Recombinant hbsag of the wild-type and the g145r escape mutant, included in the new multivalent vaccine against hepatitis b virus, dramatically differ in their effects …
MV Konopleva, VN Borisova, MV Sokolova… - Vaccines, 2022 - mdpi.com
Immune-escape hepatitis B virus (HBV) mutants play an important role in HBV spread.
Recently, the multivalent vaccine Bubo®-Unigep has been developed to protect against …
Recently, the multivalent vaccine Bubo®-Unigep has been developed to protect against …
Oncogenic HBV variants and integration are present in hepatic and lymphoid cells derived from chronic HBV patients
The hepatitis B virus (HBV) is a major cause of hepatocellular carcinoma (HCC), partly
driven by viral integration and specific oncogenic HBV variants. However, the biological …
driven by viral integration and specific oncogenic HBV variants. However, the biological …
Transplantation with GXHPC1 for liver cirrhosis: phase 1 trial
KC Huang, MH Chuang, ZS Lin, YC Lin… - Cell …, 2019 - journals.sagepub.com
Currently, the only effective therapy for cirrhosis of the liver is liver transplantation. However,
finding a compatible liver is difficult due to the low supply of healthy livers and the ever …
finding a compatible liver is difficult due to the low supply of healthy livers and the ever …