Gene therapy provides a promising strategy for curing monogenetic disorders and complex
diseases. However, there are challenges associated with the use of viral delivery vectors …

Cancer can be defined as an irregular functioning of the cell cycle that results in a
progressive loss of cell differentiation and uncontrolled cell growth. Moreover, despite …

Identifying metabolic steps that are specifically required for the survival of cancer cells but
are dispensable in normal cells remains a challenge. Here we report a therapeutic …

Cell-penetrating peptides (CPPs), developed for more than 30 years, are still being
extensively studied due to their excellent delivery performance. Compared with other …

One in three cancer deaths worldwide are caused by gastric and colorectal cancer
malignancies. Although the incidence and fatality rates differ significantly from country to …

Human nuclear receptors (NRs) are a family of forty-eight transcription factors that modulate
gene expression both spatially and temporally. Numerous biochemical, physiological, and …

Novel mononuclear complexes 2–8 derived from hybrid Urea Schiff base HL were
synthesized using various metal Ni 2+, Fe 3+, Cu 2+, Co 2+, Mn 2+, Zn 2+, and Cr 3+. The …

As with every new technology, safety demonstration is a critical component of bringing
products to market and gaining public acceptance for cultured meat and seafood. This …

Aortic aneurysm and dissection (AAD) are a group of insidious and lethal cardiovascular
diseases that characterized by seriously threatening the life and health of people, but lack …

Abnormal tryptophan metabolism is linked to cancer and neurodegenerative diseases, and
tryptophan metabolites have been reported as potential prostate cancer (PCa) biomarkers …