Treatment trials in young patients with chronic obstructive pulmonary disease and pre–chronic obstructive pulmonary disease patients: time to move forward

FJ Martinez, A Agusti, BR Celli, MLK Han… - American journal of …, 2022 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is the end result of a series of dynamic and
cumulative gene–environment interactions over a lifetime. The evolving understanding of …

Personalized medicine for patients with COPD: where are we?

FME Franssen, P Alter, N Bar… - … journal of chronic …, 2019 - Taylor & Francis
Chronic airflow limitation is the common denominator of patients with chronic obstructive
pulmonary disease (COPD). However, it is not possible to predict morbidity and mortality of …

Association between long-term exposure to ambient air pollution and change in quantitatively assessed emphysema and lung function

M Wang, CP Aaron, J Madrigano, EA Hoffman… - Jama, 2019 - jamanetwork.com
Importance While air pollutants at historical levels have been associated with cardiovascular
and respiratory diseases, it is not known whether exposure to contemporary air pollutant …

CT-definable subtypes of chronic obstructive pulmonary disease: a statement of the Fleischner Society

DA Lynch, JHM Austin, JC Hogg, PA Grenier… - Radiology, 2015 - pubs.rsna.org
The purpose of this statement is to describe and define the phenotypic abnormalities that
can be identified on visual and quantitative evaluation of computed tomographic (CT) …

CT-based visual classification of emphysema: association with mortality in the COPDGene study

DA Lynch, CM Moore, C Wilson, D Nevrekar… - Radiology, 2018 - pubs.rsna.org
Purpose To determine whether visually assessed patterns of emphysema at CT might
provide a simple assessment of mortality risk among cigarette smokers. Materials and …

Machine learning and prediction of all-cause mortality in COPD

M Moll, D Qiao, EA Regan, GM Hunninghake, BJ Make… - Chest, 2020 - Elsevier
Background COPD is a leading cause of mortality. Research Question We hypothesized that
applying machine learning to clinical and quantitative CT imaging features would improve …

[HTML][HTML] Biomarkers of progression of chronic obstructive pulmonary disease (COPD)

JG Shaw, A Vaughan, AG Dent, PE O'Hare… - Journal of thoracic …, 2014 - ncbi.nlm.nih.gov
Disease progression of chronic obstructive pulmonary disease (COPD) is variable, with
some patients having a relatively stable course, while others suffer relentless progression …

The role of chest computed tomography in the evaluation and management of the patient with chronic obstructive pulmonary disease

WW Labaki, CH Martinez, FJ Martinez… - American journal of …, 2017 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) exhibits significant heterogeneity in its
clinical presentation and rate of disease progression among affected individuals, owing at …

Chest CT‐assessed comorbidities and all‐cause mortality risk in COPD patients in the BODE cohort

A Ezponda, C Casanova, M Divo, M Marín‐Oto… - …, 2022 - Wiley Online Library
Background and objective The availability of chest computed tomography (CT) imaging can
help diagnose comorbidities associated with chronic obstructive pulmonary disease …

[HTML][HTML] Relationship between lung function and quantitative computed tomographic parameters of airway remodeling, air trapping, and emphysema in patients with …

RA Hartley, BL Barker, C Newby, M Pakkal… - Journal of Allergy and …, 2016 - Elsevier
Background There is a paucity of studies comparing asthma and chronic obstructive
pulmonary disease (COPD) based on thoracic quantitative computed tomographic (QCT) …