After 40 years of development, inductively coupled plasma-mass spectrometry (ICP-MS) can
hardly be considered as a novel technique anymore. ICP-MS has become the reference …

Mass cytometry (cytometry by time-of-flight detection [CyTOF]) is a bioanalytical technique
that enables the identification and quantification of diverse features of cellular systems with …

Single-cell (SC) analysis provides unique insight into individual cell dynamics and cell-to-
cell heterogeneity. Here, we utilize trapped ion mobility separation coupled with dual …

High-grade serous ovarian cancer (HGSOC) is the most lethal gynecological malignancy. Its
diagnosis at advanced stage compounded with its excessive genomic and cellular …

Metals have a fundamental role in microbiology, and accurate methods are needed for their
identification and quantification. The inability to assess cellular heterogeneity is considered …

CRISPR/Cas technology has greatly pushed the development of genome editing and
bioanalytical sensors after its unique endonuclease activity was reported. Especially, the …

The sensitive and accurate determination of macromolecular biomarkers is in high demand
for clinical diagnosis. Mass spectrometric immunoassay (MSIA) combines the advantages of …

A 2D flow cytometry platform, known as CytoLM Plus, was developed for multi-parameter
single-cell analysis. Single particles or cells after hydrodynamic alignment in a microfluidic …

Revealing multiple biomolecules in the physiopathological environment simultaneously is
crucial in biological and biomedical research. Mass spectrometry (MS) features unique …

The elemental analysis in disease diagnosis and biomedicine screening generally aims at
alleviating the difficulties of sample pretreatment techniques, elucidating the distribution and …