The innate immune response provides the first line of defense against invading pathogens,
and immune disorders cause a variety of diseases. The fruit fly Drosophila melanogaster …

Insects combat infection by mounting powerful immune responses that are mediated by
hemocytes, the fat body, the midgut, the salivary glands and other tissues. Foreign …

In this FlyBook chapter, we present a survey of the current literature on the development of
the hematopoietic system in Drosophila. The Drosophila blood system consists entirely of …

To combat infection, the fruit fly Drosophila melanogaster relies on multiple innate defense
reactions, many of which are shared with higher organisms. These reactions include the use …

▪ Abstract Infection in insects stimulates a complex defensive response. Recognition of
pathogens may be accomplished by plasma or hemocyte proteins that bind specifically to …

We have investigated the blood cell types present in Drosophila at postembryonic stages
and have analysed their modifications during development and under immune conditions …

The NF-κB-like Relish gene is complex, with four transcripts that are all located within an
intron of the Nmdmc gene. Using deletion mutants, we show that Relish is specifically …

Blood development in Drosophila melanogaster shares several interesting features with
hematopoiesis in vertebrates, including spatiotemporal regulation as well as the use of …

Classification of insect larvae circulating haemocytes is the subject of controversy, and the
terminology used to designate each cellular type is often different from one species to …

Innate immune responses are mediated by the activation of various signaling processes.
Here, we describe our current knowledge on Janus kinase (JAK)/signal transducers and …