Schistosomiasis is the most important helminthiasis worldwide in terms of morbidity and
mortality. Most of the infections occurs in Africa, which about two thirds are caused by …

Schistosomiasis is a neglected tropical disease that infects 240 million people. With no
vaccines and only one drug available, new therapeutic targets are needed. The causative …

Schistosome parasites kill 250,000 people every year. Treatment of schistosomiasis relies
on the drug praziquantel. Unfortunately, a scarcity of molecular tools has hindered the …

Recent reports of CRISPR/Cas9 genome editing in parasitic helminths open up new
avenues for research on these dangerous pathogens. However, the complex morphology …

Schistosomes cause morbidity and death throughout the developing world due to the
massive numbers of eggs female worms deposit into the blood of their host. Studies dating …

Schistosomes are parasitic flatworms causing one of the most prevalent infectious diseases
from which millions of people are currently suffering. These parasites have high fecundity …

The trematode parasite Schistosoma mansoni causes schistosomiasis, which affects over
200 million people worldwide. Schistosomes are dioecious, with egg laying depending on …

P53 is a widely studied tumor suppressor that plays important roles in cell-cycle regulation,
cell death, and DNA damage repair. P53 is found throughout metazoans, even in …

Background The consequences of the earth's daily rotation have led to 24-h biological
rhythms in most organisms. Even some parasites are known to have daily rhythms, which …

α-galactosidase (α-GAL) and α-N-acetylgalactosaminidase (α-NAGAL) are two glycosyl
hydrolases responsible for maintaining cellular homeostasis by regulating glycan substrates …