Successful development of treatments for non-alcoholic fatty liver disease and its
progressive form, non-alcoholic steatohepatitis (NASH), has been challenging. Because …

Exosomes belong to a subpopulation of extracellular vesicles secreted by the dynamic
multistep endocytosis process and carry diverse functional molecular cargoes, including …

Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Exosomes are nanoscale-sized membrane vesicles secreted by almost all cell types into the
extracellular environment upon fusion of multivesicular bodies and plasma membrane …

Inflammasomes are multiprotein complexes that can sense danger signals and activate
caspase-1 to mediate pro-inflammatory cytokines release and pyroptotic cell death. There …

The activation of stimulator of interferon genes (STING) and NOD-like receptor protein 3
(NLRP3) inflammasome-mediated pyroptosis signaling pathways represent two distinct …

The regenerative function of liver can be destroyed by viral infection, drug poisoning and
tumorigenesis, resulting in irreversible damage. Numerous approaches in promoting liver …

Osteoarthritis (OA) is a degenerative joint disorder causing pain and functional disability.
Emerging evidence reveals that circular RNAs (circRNAs) play essential roles in OA …

The liver can succumb to oxidant damage during the development of chronic liver diseases.
Despite their physiological relevance to hepatic homeostasis, excessive reactive …

Background Dynamic contrast-enhanced (DCE) photoacoustic (PA) imaging (PAI) is a novel
noninvasive imaging modality that uses the differences in optical absorption of …