ERp57/PDIA3: new insight
S Chichiarelli, F Altieri, G Paglia, E Rubini… - Cellular & Molecular …, 2022 - Springer
The ERp57/PDIA3 protein is a pleiotropic member of the PDIs family and, although
predominantly located in the endoplasmic reticulum (ER), has indeed been found in other …
predominantly located in the endoplasmic reticulum (ER), has indeed been found in other …
Mechanisms of translocation of ER chaperones to the cell surface and immunomodulatory roles in cancer and autoimmunity
Endoplasmic reticulum (ER) chaperones (eg, calreticulin, heat shock proteins, and
isomerases) perform a multitude of functions within the ER. However, many of these …
isomerases) perform a multitude of functions within the ER. However, many of these …
Multifunctional molecule ERp57: From cancer to neurodegenerative diseases
A Hettinghouse, R Liu, C Liu - Pharmacology & therapeutics, 2018 - Elsevier
The protein disulfide isomerase (PDI) gene family is a protein family classically
characterized by endoplasmic reticulum (ER) localization and isomerase and redox activity …
characterized by endoplasmic reticulum (ER) localization and isomerase and redox activity …
[HTML][HTML] PDIA3 correlates with clinical malignant features and immune signature in human gliomas
Since therapeutic strategies are limited in gliomas, new molecules or biomarkers are
essential for diagnosis and therapy. Here, we investigated expression of protein disulfide …
essential for diagnosis and therapy. Here, we investigated expression of protein disulfide …
[PDF][PDF] PDIA3 and PDIA6 gene expression as an aggressiveness marker in primary ductal breast cancer
FS Ramos, LT Serino, CM Carvalho, RS Lima… - Genet Mol …, 2015 - funpecrp.com.br
Changes in the expression of the protein disulfide isomerase genes PDIA3and PDIA6may
increase endoplasmic reticulum stress, leading to cellular instability and neoplasia. We …
increase endoplasmic reticulum stress, leading to cellular instability and neoplasia. We …
Roles of protein disulfide isomerase in breast cancer
Simple Summary Triple-negative breast cancer (TNBC) is the most aggressive subtype of
breast cancer and has a poor prognosis and higher recurrence rate due to ineffective …
breast cancer and has a poor prognosis and higher recurrence rate due to ineffective …
PDIA3 expression in glioblastoma modulates macrophage/microglia pro-tumor activation
M Chiavari, GMP Ciotti, F Canonico, F Altieri… - International Journal of …, 2020 - mdpi.com
The glioblastoma (GB) microenvironment includes cells of the innate immune system
identified as glioma-associated microglia/macrophages (GAMs) that are still poorly …
identified as glioma-associated microglia/macrophages (GAMs) that are still poorly …
Insulin‐like growth factor and epidermal growth factor signaling in breast cancer cell growth: focus on endocrine resistant disease
K Voudouri, A Berdiaki, M Tzardi… - Analytical cellular …, 2015 - Wiley Online Library
Breast cancer is the most common type of cancer for women worldwide with a lifetime risk
amounting to a staggering total of 10%. It is well established that the endogenous synthesis …
amounting to a staggering total of 10%. It is well established that the endogenous synthesis …
Upregulation of ERp57 promotes clear cell renal cell carcinoma progression by initiating a STAT3/ILF3 feedback loop
Y Liu, JX Wang, ZY Nie, Y Wen, XJ Jia… - Journal of Experimental …, 2019 - Springer
Background ERp57 dysfunction has been shown to contribute to tumorigenesis in multiple
malignances. However, the role of ERp57 in clear cell renal carcinoma (ccRCC) remains …
malignances. However, the role of ERp57 in clear cell renal carcinoma (ccRCC) remains …
[HTML][HTML] Insights into the role of ERp57 in cancer
D Song, H Liu, J Wu, X Gao, J Hao, D Fan - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
Endoplasmic reticulum resident protein 57 (ERp57) has a molecular weight of 57 kDa,
belongs to the protein disulfide-isomerase (PDI) family, and is primarily located in the …
belongs to the protein disulfide-isomerase (PDI) family, and is primarily located in the …