Brown adipose tissue—a translational perspective

AC Carpentier, DP Blondin, F Haman… - Endocrine …, 2023 - academic.oup.com
Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …

Brown adipose tissue, diet-induced thermogenesis, and thermogenic food ingredients: from mice to men

M Saito, M Matsushita, T Yoneshiro… - Frontiers in …, 2020 - frontiersin.org
Since the recent rediscovery of brown adipose tissue (BAT) in adult humans, this
thermogenic tissue has been attracting increasing interest. The inverse relationship between …

Incendiary leptin

P Seoane-Collazo, N Martínez-Sánchez, E Milbank… - Nutrients, 2020 - mdpi.com
Leptin is a hormone released by adipose tissue that plays a key role in the control of energy
homeostasis through its binding to leptin receptors (LepR), mainly expressed in the …

Microfluidization trends in the development of nanodelivery systems and applications in chronic disease treatments

P Ganesan, G Karthivashan, SY Park… - International journal of …, 2018 - Taylor & Francis
Plant bioactive compounds are known for their extensive health benefits and therefore have
been used for generations in traditional and modern medicine to improve the health of …

Browning of adipocytes: A potential therapeutic approach to obesity

V Schirinzi, C Poli, C Berteotti, A Leone - Nutrients, 2023 - mdpi.com
The increasing prevalence of overweight and obesity suggests that current strategies based
on diet, exercise, and pharmacological knowledge are not sufficient to tackle this epidemic …

Role of human brown fat in obesity, metabolism and cardiovascular disease: strategies to turn up the heat

JR Ruiz, B Martinez-Tellez, G Sanchez-Delgado… - Progress in …, 2018 - Elsevier
Human brown adipose tissue (BAT) was re-discovered in 2009 by several independent
groups, who showed that it is present and active in adults, as judged from the profound …

Brown and brite: the fat soldiers in the anti-obesity fight

S Srivastava, RL Veech - Frontiers in physiology, 2019 - frontiersin.org
Brown adipose tissue (BAT) is proposed to maintain thermal homeostasis through
dissipation of chemical energy as heat by the uncoupling proteins (UCPs) present in their …

Nutritional regulation of human brown adipose tissue

KJ Suchacki, RH Stimson - Nutrients, 2021 - mdpi.com
The recent identification of brown adipose tissue in adult humans offers a new strategy to
increase energy expenditure to treat obesity and associated metabolic disease. While white …

Brown adipose tissue: multimodality evaluation by PET, MRI, infrared thermography, and whole‐body calorimetry (TACTICAL‐II)

L Sun, S Verma, N Michael, SP Chan, J Yan… - …, 2019 - Wiley Online Library
Objective This study aimed to compare the associations of positron emission tomography
(PET), magnetic resonance (MR), and infrared thermography (IRT) imaging modalities with …

Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes

C Clemmensen, S Jall, M Kleinert, C Quarta… - Nature …, 2018 - nature.com
Pharmacological stimulation of brown adipose tissue (BAT) thermogenesis to increase
energy expenditure is progressively being pursued as a viable anti-obesity strategy. Here …