Label-free optical imaging employs natural and non-destructive approaches to visualize
biomedical samples for both biological assays and clinical diagnosis. At present, this field …

During microsurgery, en face imaging of the surgical field through the operating microscope
limits the surgeon's depth perception and visualization of instruments and sub-surface …

Since the inception of optical coherence tomography (OCT), advancements in imaging
system design and handheld probes have allowed for numerous advancements in disease …

Introduction Tumor detection and visualization plays a key role in the clinical workflow of a
patient with suspected cancer, both in the diagnosis and treatment. Several optical imaging …

Sentinel lymph node identification by near infrared (NIR) fluorescence with indocyanine
green (ICG) is recognized in the literature as a useful technique. NIR fluorescence …

Thin tissue slice based histology has been used as a gold standard for disease diagnosis
since over a hundred years ago. However, histopathological evaluation on two-dimensional …

With the advent of Minimally Invasive Surgery (MIS), intra-operative imaging has become
crucial for surgery and therapy guidance, allowing to partially compensate for the lack of …

Background Although traditional intraoperative assessments (ie, frozen sections) may lower
reoperation rates in patients with breast cancer, time/tissue limitations and accuracy …

Biophotonic imaging has revolutionized the operation room by providing surgeons
intraoperative image-guidance to diagnose tumors more efficiently and to resect tumors with …

We report the first application of compression optical coherence elastography (C-OCE) to
evaluate both linear and nonlinear elastic properties of lymph nodes (LNs) for assessing …