[HTML][HTML] Therapeutic potentials of CRISPR-Cas genome editing technology in human viral infections
S Najafi, SC Tan, S Aghamiri, P Raee… - Biomedicine & …, 2022 - Elsevier
Viral infections are a common cause of morbidity worldwide. The emergence of Coronavirus
Disease 2019 (COVID-19) has led to more attention to viral infections and finding novel …
Disease 2019 (COVID-19) has led to more attention to viral infections and finding novel …
Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy
M Matsuoka, KT Jeang - Oncogene, 2011 - nature.com
The human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus discovered to be
causative of a human cancer, adult T-cell leukemia. The transforming entity of HTLV-1 has …
causative of a human cancer, adult T-cell leukemia. The transforming entity of HTLV-1 has …
HTLV-1 bZIP Factor Induces T-Cell Lymphoma and Systemic Inflammation In Vivo
Y Satou, J Yasunaga, T Zhao, M Yoshida… - PLoS …, 2011 - journals.plos.org
Human T-cell leukemia virus type 1 (HTLV-1) is the causal agent of a neoplastic disease of
CD4+ T cells, adult T-cell leukemia (ATL), and inflammatory diseases including HTLV-1 …
CD4+ T cells, adult T-cell leukemia (ATL), and inflammatory diseases including HTLV-1 …
Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells
Viruses causing chronic infection artfully manipulate infected cells to enable viral
persistence in vivo under the pressure of immunity. Human T-cell leukemia virus type 1 …
persistence in vivo under the pressure of immunity. Human T-cell leukemia virus type 1 …
HTLV-1 infection and adult T-cell leukemia/lymphoma—a tale of two proteins: tax and HBZ
HTLV-1 (Human T-cell lymphotropic virus type 1) is a complex human delta retrovirus that
currently infects 10–20 million people worldwide. While HTLV-1 infection is generally …
currently infects 10–20 million people worldwide. While HTLV-1 infection is generally …
Targeting the HTLV-I-regulated BATF3/IRF4 transcriptional network in adult T cell leukemia/lymphoma
M Nakagawa, AL Shaffer, M Ceribelli, M Zhang… - Cancer Cell, 2018 - cell.com
Adult T cell leukemia/lymphoma (ATLL) is a frequently incurable disease associated with the
human lymphotropic virus type I (HTLV-I). RNAi screening of ATLL lines revealed that their …
human lymphotropic virus type I (HTLV-I). RNAi screening of ATLL lines revealed that their …
HTLV-1 bZIP factor: the key viral gene for pathogenesis
M Matsuoka, JM Mesnard - Retrovirology, 2020 - Springer
Human T cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL)
and inflammatory diseases. The HTLV-1 bZIP factor (HBZ) gene is constantly expressed in …
and inflammatory diseases. The HTLV-1 bZIP factor (HBZ) gene is constantly expressed in …
Multifaceted functions and roles of HBZ in HTLV-1 pathogenesis
G Ma, J Yasunaga, M Matsuoka - Retrovirology, 2016 - Springer
Human T cell leukemia virus type 1 (HTLV-1) is an oncogenic retrovirus responsible for the
development of adult T-cell leukemia (ATL). Although HTLV-1 harbors an oncogene, tax …
development of adult T-cell leukemia (ATL). Although HTLV-1 harbors an oncogene, tax …
The HBZ gene, a key player in HTLV-1 pathogenesis
M Matsuoka, PL Green - Retrovirology, 2009 - Springer
Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL)
and is also associated with a variety of lymphocyte-mediated diseases. The HTLV-1 basic …
and is also associated with a variety of lymphocyte-mediated diseases. The HTLV-1 basic …