Despite effective antiretroviral therapy (ART), people living with HIV (PLWH) still present
persistent chronic immune activation and inflammation. This condition is the result of several …

Despite substantial progress in the development of antiretroviral regimens that durably
suppress Human Immunodeficiency Virus (HIV) infection, new agents that maintain high …

Background Tenofovir disoproxil fumarate can cause renal and bone toxic effects related to
high plasma tenofovir concentrations. Tenofovir alafenamide is a novel tenofovir prodrug …

Objective Quantify proportion of human immunodeficiency virus (HIV)–infected patients with
specific comorbidities receiving healthcare coverage from commercial, Medicaid, and …

Background Antiretroviral regimens containing tenofovir disoproxil fumarate have been
associated with renal toxicity and reduced bone mineral density. Tenofovir alafenamide is a …

Context New trial data and drug regimens that have become available in the last 2 years
warrant an update to guidelines for antiretroviral therapy (ART) in human immunodeficiency …

With the adoption of combination antiretroviral therapy (ART), most HIV-infected individuals
in care are on five or more medications and at risk of harm from polypharmacy, a risk that …

Abstract Background. Daily preexposure prophylaxis (PrEP) with oral emtricitabine and
tenofovir disoproxil fumarate (FTC/TDF) decreases the risk of human immunodeficiency …

Osteoporosis is a frequently observed complication in patients with chronic liver disease,
particularly liver cirrhosis and cholestatic liver diseases. In addition, osteoporosis is critical in …

Background Problems associated with lifelong antiretroviral therapy, such as need for strict
adherence, drug-related toxic effects, difficulties with treatment schedules, and cost, mean …