[HTML][HTML] Microbiome dysbiosis: A pathological mechanism at the intersection of obesity and glaucoma

S Pezzino, M Sofia, LP Greco, G Litrico… - International Journal of …, 2023 - mdpi.com
The rate at which obesity is becoming an epidemic in many countries is alarming. Obese
individuals have a high risk of developing elevated intraocular pressure and glaucoma …

[HTML][HTML] The role of the microbiota in glaucoma

L Huang, Y Hong, X Fu, H Tan, Y Chen, Y Wang… - Molecular Aspects of …, 2023 - Elsevier
Glaucoma is a common irreversible vision loss disorder because of the gradual loss of
retinal ganglion cells (RGCs) and the optic nerve axons. Major risk factors include elder age …

[HTML][HTML] Phenotypic and genetic links between body fat measurements and primary open-angle glaucoma

SS Rong, X Yu - International Journal of Molecular Sciences, 2023 - mdpi.com
The phenotypic and genetic links between body fat phenotypes and primary open-angle
glaucoma (POAG) are unclear. We conducted a meta-analysis of relevant longitudinal …

[HTML][HTML] Presence and severity of migraine is associated with development of primary open angle glaucoma: A population-based longitudinal cohort study

K Ohn, K Han, JI Moon, Y Jung - Plos one, 2023 - journals.plos.org
Purpose To examine the association between the presence and severity of migraine and
development of primary open-angle glaucoma (POAG) using a nationwide population …

[HTML][HTML] Potentially compromised systemic and local lactate metabolic balance in glaucoma, which could increase retinal glucose and glutamate concentrations

M Arai-Okuda, Y Murai, H Maeda, A Kanamori… - Scientific Reports, 2024 - nature.com
To investigate the association between lactate metabolism and glaucoma, we conducted a
multi-institutional cross-sectional clinical study and a retinal metabolomic analysis of mice …

[HTML][HTML] Causal factors in primary open angle glaucoma: a phenome-wide Mendelian randomisation study

TH Julian, Z Girach, E Sanderson, H Guo, J Yu… - Scientific Reports, 2023 - nature.com
Primary open angle glaucoma (POAG) is a chronic, adult-onset optic neuropathy associated
with characteristic optic disc and/or visual field changes. With a view to identifying modifiable …

[HTML][HTML] Cannabis use and the risk of primary open-angle glaucoma: a Mendelian randomization study

A Katsimpris, SE Baumeister, H Baurecht, AJ Tatham… - Scientific Reports, 2023 - nature.com
Several observational studies have investigated the association between cannabis use and
intraocular pressure, but its association with primary open-angle glaucoma (POAG) remains …

Social history and glaucoma progression: the effect of body mass index, tobacco and alcohol consumption on the rates of structural change in patients with glaucoma

AA Youssif, NA Onyekaba, R Naithani… - British Journal of …, 2024 - bjo.bmj.com
Background/aims Although obesity, tobacco and alcohol consumption were linked to the
progression of numerous chronic diseases, an association of these social history aspects …

[HTML][HTML] Differences in Factors Associated With Glaucoma Progression With Lower Normal Intraocular Pressure in Superior and Inferior Halves of the Optic Nerve …

R Asaoka, R Sakata, T Yoshitomi… - … Vision Science & …, 2023 - tvst.arvojournals.org
Purpose: The purpose of this study was to investigate risk factors for progression in the
superior and inferior hemi-visual fields (hemi-VFs) and the corresponding hemi-disc/retinas …

[HTML][HTML] Evaluation of the Observational Associations and Shared Genetics Between Glaucoma With Depression and Anxiety

X Zhang, Y Liang, Y Huang, S Liu, Q Li… - … & Visual Science, 2024 - tvst.arvojournals.org
Purpose: Glaucoma, a leading cause of blindness worldwide, is suspected to exhibit a
notable association with psychological disturbances. This study aimed to investigate …