Novel diagnostic biomarkers in colorectal cancer

AL Zygulska, P Pierzchalski - International journal of molecular sciences, 2022 - mdpi.com
Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …

The diagnostic significance of CDH17-positive circulating tumor cells in patients with colorectal cancer

XM Pei, HT Wong, SSM Ng, WW Leung… - Expert Review of …, 2023 - Taylor & Francis
Background Colorectal cancer (CRC) is the second leading cause of cancer deaths in Hong
Kong. We tested the hypothesis that circulating tumor cell (CTC) analysis by ARB101 …

Diagnostic and prognostic roles of CDX2 immunohistochemical expression in colorectal cancers

HB Choi, JS Pyo, S Son, K Kim, G Kang - Diagnostics, 2022 - mdpi.com
The study is aimed to evaluate the diagnostic and prognostic role of the
immunohistochemical expression of the Caudal-type homeobox transcription factor 2 …

Integrated transcriptomics and proteomics data analysis identifies CDH17 as a key cell surface target in colorectal cancer

KK Wong - Computational Biology and Chemistry, 2023 - Elsevier
Immunotherapy development against colorectal cancer (CRC) is hindered by the lack of cell
surface target highly expressed in cancer cells but with restricted presence in normal tissues …

[HTML][HTML] Cadherin-17 (CDH17) expression in human cancer: A tissue microarray study on 18,131 tumors

F Jacobsen, R Pushpadevan, F Viehweger… - … -Research and Practice, 2024 - Elsevier
Abstract Cadherin-17 (CDH17) is a membranous cell adhesion protein predominantly
expressed in intestinal epithelial cells. CDH17 is therefore considered a possible diagnostic …

Angiopoietin‐like protein 3 promotes colorectal cancer progression and liver metastasis partly via the mitogen‐activated protein kinase 14 pathway

Y Wang, Y Yi, S Pan, Y Zhang, J Fu… - Molecular …, 2023 - Wiley Online Library
Colorectal cancer (CRC) remains one of the most common malignancies worldwide, and
liver metastasis represents a considerable challenge during CRC treatment. Aberrant …

The Role of circRNA-miRNA-mRNA Regulatory Network and its Potential Biomarker Function in Colorectal Cancer

X Fu, P Chen, H Wang - Protein and Peptide Letters, 2023 - ingentaconnect.com
Background: Revealing the process and mechanism of colorectal cancer will facilitate the
discovery of new biomarkers and contribute to the development of targeted drugs …

[HTML][HTML] Multiomics2Targets identifies targets from cancer cohorts profiled with transcriptomics, proteomics, and phosphoproteomics

EZ Deng, GB Marino, DJB Clarke, I Diamant… - Cell Reports …, 2024 - cell.com
The availability of data from profiling of cancer patients with multiomics is rapidly increasing.
However, integrative analysis of such data for personalized target identification is not trivial …

Variability in morphology and immunohistochemistry of Crohn's disease-associated small bowel neoplasms: implications of Claudin 18 and Cadherin 17 expression …

M Iwaya, M Kodama, K Abe, K Maeda, T Nakajima… - Virchows Archiv, 2024 - Springer
Aims: Inflammatory bowel disease-associated colorectal carcinomas are known to have
different morphology, immunoprofile, and genetic findings from sporadic colorectal …

[PDF][PDF] Tumor Markers of Colorectal Carcinoma: New Perspectives

AM Kabel, SM Kabel - Journal of Cancer Research, 2024 - researchgate.net
Colorectal carcinoma (CRC) represents one of the most commonly diagnosed malignant
tumors worldwide. In spite of the continuous progress in diagnostic and therapeutic tools …