Spectral and dual-energy X-ray imaging for medical applications

E Fredenberg - Nuclear Instruments and Methods in Physics Research …, 2018 - Elsevier
Spectral imaging is an umbrella term for energy-resolved X-ray imaging in medicine. The
technique makes use of the energy dependence of X-ray attenuation to either increase the …

Discriminating solitary cysts from soft tissue lesions in mammography using a pretrained deep convolutional neural network

T Kooi, B van Ginneken, N Karssemeijer… - Medical …, 2017 - Wiley Online Library
Purpose It is estimated that 7% of women in the western world will develop palpable breast
cysts in their lifetime. Even though cysts have been correlated with risk of developing breast …

An all-in-one nanoparticle (AION) contrast agent for breast cancer screening with DEM-CT-MRI-NIRF imaging

JC Hsu, PC Naha, KC Lau, P Chhour, R Hastings… - Nanoscale, 2018 - pubs.rsc.org
Conventional X-ray mammography has low diagnostic sensitivity for women with dense
breasts. As a result, alternative contrast-enhanced screening tools such as dual energy …

Renally excretable and size-tunable silver sulfide nanoparticles for dual-energy mammography or computed tomography

JC Hsu, ED Cruz, KC Lau, M Bouché, J Kim… - Chemistry of …, 2019 - ACS Publications
Significant effort has been focused on developing renally clearable nanoparticle agents
since efficient renal clearance is important for eventual clinical translation. Silver sulfide …

Breast cancer assessment with pulse-echo speed of sound ultrasound from intrinsic tissue reflections: Proof-of-concept

L Ruby, SJ Sanabria, K Martini, KJ Dedes… - Investigative …, 2019 - journals.lww.com
Purpose The aim of this study was to differentiate malignant and benign solid breast lesions
with a novel ultrasound (US) technique, which measures speed of sound (SoS) using …

Measurement of breast-tissue x-ray attenuation by spectral imaging: fresh and fixed normal and malignant tissue

E Fredenberg, P Willsher, E Moa… - Physics in Medicine …, 2018 - iopscience.iop.org
Abstract Knowledge of x-ray attenuation is essential for developing and evaluating x-ray
imaging technologies. In mammography, measurement of breast density, dose estimation …

Influence of Acquisition Parameters on Silver Sulfide Nanoparticle Contrast in Photon-Counting Digital Mammography: A Phantom Study

JC Hsu, KC Lau, D Barragan… - ACS Applied Nano …, 2024 - ACS Publications
Photon-counting mammography is an emerging modality that allows for spectral imaging
and provides a differentiation of material compositions. The development of photon-counting …

Investigating the feasibility of classifying breast microcalcifications using photon‐counting spectral mammography: a simulation study

B Ghammraoui, SJ Glick - Medical physics, 2017 - Wiley Online Library
Purpose A dual‐energy material decomposition method using photon‐counting spectral
mammography was investigated as a non‐invasive diagnostic approach to differentiate …

Photon counting performance of amorphous selenium and its dependence on detector structure

J Stavro, AH Goldan, W Zhao - Journal of Medical Imaging, 2018 - spiedigitallibrary.org
Photon counting detectors (PCD) have the potential to improve x-ray imaging; however, they
are still hindered by high costs and performance limitations. By using amorphous selenium …

Measurement of breast-tissue x-ray attenuation by spectral mammography: solid lesions

E Fredenberg, F Kilburn-Toppin… - Physics in Medicine …, 2016 - iopscience.iop.org
Abstract Knowledge of x-ray attenuation is essential for developing and evaluating x-ray
imaging technologies. For instance, techniques to distinguish between cysts and solid …