Developing novel treatments for alcohol use disorders (AUDs) is of paramount importance
for improving patient outcomes and alleviating the suffering related to the disease. A better …

Human adolescence is a period of development characterized by wide ranging emotions
and behavioral risk taking, including binge drinking. These behavioral manifestations of …

Neuroimmune pathways regulate brain function to influence complex behavior and play a
role in several neuropsychiatric diseases, including alcohol use disorder (AUD). In …

A key feature of compulsive alcohol drinking is continuing to drink despite negative
consequences. To examine the changes in neural activity that underlie this behavior …

Alcohol use disorder (AUD) affects all sexes, however women who develop AUD may be
particularly susceptible to cravings and other components of the disease. While many brain …

The central nucleus of the amygdala (CeA) is implicated in alcohol use disorder (AUD) and
AUD-associated plasticity. The CeA is a primarily GABAergic nucleus that is subdivided into …

Forced abstinence (FA) from alcohol has been shown to produce a variety of anxiety-and
depression-like symptoms in animal models. Somatostatin (SST) neurons, a subtype of …

Astrocytes are integral components of synaptic transmission, and their dysfunction leads to
neuropsychiatric disorders such as anxiety and depression. Liver X receptor β (LXRβ) is …

After experiencing a traumatic event people often turn to alcohol to cope with symptoms. In
those with post-traumatic stress disorder (PTSD) and a co-occurring alcohol use disorder …

Adolescent drug consumption has increased risks to the individual compared to
consumption in adulthood, due to the likelihood of long-term and permanent behavioral and …