Cerebral amyloid angiopathy and Alzheimer disease—one peptide, two pathways
SM Greenberg, BJ Bacskai… - Nature Reviews …, 2020 - nature.com
The shared role of amyloid-β (Aβ) deposition in cerebral amyloid angiopathy (CAA) and
Alzheimer disease (AD) is arguably the clearest instance of crosstalk between …
Alzheimer disease (AD) is arguably the clearest instance of crosstalk between …
[HTML][HTML] Ultra-slow oscillations in fMRI and resting-state connectivity: neuronal and vascular contributions and technical confounds
Summary Ultra-slow,∼ 0.1-Hz variations in the oxygenation level of brain blood are widely
used as an fMRI-based surrogate of" resting-state" neuronal activity. The temporal …
used as an fMRI-based surrogate of" resting-state" neuronal activity. The temporal …
[HTML][HTML] Vasomotion as a driving force for paravascular clearance in the awake mouse brain
SJ van Veluw, SS Hou, M Calvo-Rodriguez… - Neuron, 2020 - cell.com
Paravascular drainage of solutes, including β-amyloid (Aβ), appears to be an important
process in brain health and diseases such as Alzheimer's disease (AD) and cerebral …
process in brain health and diseases such as Alzheimer's disease (AD) and cerebral …
[HTML][HTML] Optical imaging and spectroscopy for the study of the human brain: status report
This report is the second part of a comprehensive two-part series aimed at reviewing an
extensive and diverse toolkit of novel methods to explore brain health and function. While …
extensive and diverse toolkit of novel methods to explore brain health and function. While …
Vascular and neural basis of the BOLD signal
PJ Drew - Current opinion in neurobiology, 2019 - Elsevier
Highlights•The architecture of the cerebral vasculature sculpts the hemodynamics
response.•The BOLD signal is correlated with increases in gamma-band power in the LFP …
response.•The BOLD signal is correlated with increases in gamma-band power in the LFP …
[HTML][HTML] Mapping the subcortical connectivity of the human default mode network
The default mode network (DMN) mediates self-awareness and introspection, core
components of human consciousness. Therapies to restore consciousness in patients with …
components of human consciousness. Therapies to restore consciousness in patients with …
[HTML][HTML] Imaging perivascular space structure and function using brain MRI
In this article, we provide an overview of current neuroimaging methods for studying
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing …
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing …
[HTML][HTML] Arterial vasodilation drives convective fluid flow in the brain: a poroelastic model
The movement of fluid into, through, and out of the brain plays an important role in clearing
metabolic waste. However, there is controversy regarding the mechanisms driving fluid …
metabolic waste. However, there is controversy regarding the mechanisms driving fluid …
A critical assessment of data quality and venous effects in sub-millimeter fMRI
Advances in hardware, pulse sequences, and reconstruction techniques have made it
possible to perform functional magnetic resonance imaging (fMRI) at sub-millimeter …
possible to perform functional magnetic resonance imaging (fMRI) at sub-millimeter …
Whole-brain mapping of effective connectivity by fMRI with cortex-wide patterned optogenetics
Functional magnetic resonance imaging (fMRI) with optogenetic neural manipulation is a
powerful tool that enables brain-wide mapping of effective functional networks. To achieve …
powerful tool that enables brain-wide mapping of effective functional networks. To achieve …