Barriers and strategies of cationic liposomes for cancer gene therapy

C Liu, L Zhang, W Zhu, R Guo, H Sun, X Chen… - … Therapy Methods & …, 2020 - cell.com
Cationic liposomes (CLs) have been regarded as the most promising gene delivery vectors
for decades with the advantages of excellent biodegradability, biocompatibility, and high …

Polyethylene glycol-mediated fusion of extracellular vesicles with cationic liposomes for the design of hybrid delivery systems

D Mukherjee, D Paul, S Sarker, MN Hasan… - ACS Applied Bio …, 2021 - ACS Publications
To realize a customizable biogenic delivery platform, herein we propose combining cell-
derived extracellular vesicles (EVs) derived from breast cancer cell line MCF-7 with synthetic …

Transferrin-conjugated liposomes loaded with carnosic acid inhibit liver cancer growth by inducing mitochondria-mediated apoptosis

X Liu, S Dong, M Dong, Y Li, Z Sun, X Zhang… - International Journal of …, 2021 - Elsevier
Our previous studies have proven that carnosic acid (CA) induces apoptosis of liver cancer
cells. However, the poor chemical properties of CA limit its in vivo anti-cancer effects. In this …

Molecular co-localization of multiple drugs in a nanoscopic delivery vehicle for potential synergistic remediation of multi-drug resistant bacteria

A Banerjee, D Mukherjee, A Bera, R Ghosh… - Scientific reports, 2022 - nature.com
Anti-microbial resistant infection is predicted to be alarming in upcoming years. In the
present study, we proposed co-localization of two model drugs viz., rifampicin and …

A mechanoelastic glimpse on hyaluronan-coated extracellular vesicles

D Paul, A Paul, D Mukherjee, S Saroj… - The Journal of …, 2022 - ACS Publications
Cancer cells secrete extracellular vesicles (EVs) covered with a carbohydrate polymer,
hyaluronan (HA), linked to tumor malignancy. Herein, we have unravelled the contour …

Self-assembly of artificial sweetener aspartame adversely affects phospholipid membranes: plausible reason for its deleterious effects

S Nandi, S Layek, PK Nandi, N Bera, R Hazra… - Chemical …, 2021 - pubs.rsc.org
The prolonged intake of the artificial sweetener aspartame is known to have deleterious
effects. Our biophysical experimentations indicate that aspartame forms self-assembled …

[PDF][PDF] Molecular and biomolecular spectroscopy

S Ghosh, R Saha, S Sarkar, A Biswas… - Spectrochimica Acta Part …, 2023 - roderic.uv.es
ABSTRACT A naphthalimide-labeled rhodamine hydrazone derivative HL has been
synthesized, characterized and examined in metal ion recognition. It shows selective …

Structurally Dynamic Monocyte–Liposome Hybrid Vesicles as an Anticancer Drug Delivery Vehicle: A Crucial Correlation of Microscopic Elasticity and Ultrafast …

R Ghosh, L Roy, D Mukherjee, S Sarker… - The Journal of …, 2024 - ACS Publications
A biomimetic cell-based carrier system based on monocyte membranes and liposomes has
been designed to create a hybrid “Monocyte-LP” which inherits the surface antigens of the …

Decoding the kinetic pathways toward a lipid/DNA complex of alkyl alcohol cationic lipids formed in a microfluidic channel

D Mukherjee, MN Hasan, R Ghosh… - The Journal of …, 2022 - ACS Publications
Complexes of cationic liposomes with DNA have emerged as promising nonviral vectors for
delivering genetic information into cells for gene therapy. Kinetics of the liposome/DNA …

Mimicking cellular fusion in a microfluidic channel via time-resolved chemiluminescence

R Ghosh, D Mukherjee, G Ghosh, MN Hasan… - … of Photochemistry and …, 2023 - Elsevier
Cell–cell fusion is a highly regulated and dramatic cellular event which is key to cell
development. Reverse micelles (RMs) consist of nanoscopic droplets of water delimited by a …