Neutrophils in the tumor microenvironment

DR Powell, A Huttenlocher - Trends in immunology, 2016 - cell.com
Neutrophils are the first responders to sites of acute tissue damage and infection. Recent
studies suggest that in addition to neutrophil apoptosis, resolution of neutrophil inflammation …

Zebrafish models of cancer—new insights on modeling human cancer in a non-mammalian vertebrate

M Hason, P Bartůněk - Genes, 2019 - mdpi.com
Zebrafish (Danio rerio) is a valuable non-mammalian vertebrate model widely used to study
development and disease, including more recently cancer. The evolutionary conservation of …

Single-cell functional and chemosensitive profiling of combinatorial colorectal therapy in zebrafish xenografts

R Fior, V Póvoa, RV Mendes… - Proceedings of the …, 2017 - National Acad Sciences
Cancer is as unique as the person fighting it. With the exception of a few biomarker-driven
therapies, patients go through rounds of trial-and-error approaches to find the best …

Skeletal biology and disease modeling in zebrafish

K Dietrich, IAK Fiedler, A Kurzyukova… - Journal of Bone and …, 2020 - academic.oup.com
Zebrafish are teleosts (bony fish) that share with mammals a common ancestor belonging to
the phylum Osteichthyes, from which their endoskeletal systems have been inherited …

Zebrafish cancer: the state of the art and the path forward

R White, K Rose, L Zon - Nature Reviews Cancer, 2013 - nature.com
The zebrafish is a recent addition to animal models of human cancer, and studies using this
model are rapidly contributing major insights. Zebrafish develop cancer spontaneously, after …

Origin and therapies of osteosarcoma

B Moukengue, M Lallier, L Marchandet, M Baud'huin… - Cancers, 2022 - mdpi.com
Simple Summary Osteosarcoma is the most common malignant bone tumor in children, with
a 5-year survival rate ranging from 70% to 20% depending on the aggressiveness of the …

Application of animal models in cancer research: recent progress and future prospects

Z Li, W Zheng, H Wang, Y Cheng, Y Fang… - Cancer management …, 2021 - Taylor & Francis
Animal models refers to the animal experimental objects and related materials that can
simulate human body established in medical research. As the second-largest disease in …

Tissue Tolerable Plasma (TTP) induces apoptosis in pancreatic cancer cells in vitro and in vivo

LI Partecke, K Evert, J Haugk, F Doering, L Normann… - BMC cancer, 2012 - Springer
Background The rate of microscopic incomplete resections of gastrointestinal cancers
including pancreatic cancer has not changed considerably over the past years. Future intra …

Zebrafish: speeding up the cancer drug discovery process

P Letrado, I de Miguel, I Lamberto, R Díez-Martínez… - Cancer research, 2018 - AACR
Zebrafish (Danio rerio) is an ideal in vivo model to study a wide variety of human cancer
types. In this review, we provide a comprehensive overview of zebrafish in the cancer drug …

From seeing to believing: labelling strategies for in vivo cell-tracking experiments

F Progatzky, MJ Dallman, C Lo Celso - Interface focus, 2013 - royalsocietypublishing.org
Intravital microscopy has become increasingly popular over the past few decades because it
provides high-resolution and real-time information about complex biological processes …