The use of alternative strategies for enhanced nanoparticle delivery to solid tumors
M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
Nanotechnology for boosting cancer immunotherapy and remodeling tumor microenvironment: the horizons in cancer treatment
S Gao, X Yang, J Xu, N Qiu, G Zhai - ACS nano, 2021 - ACS Publications
Immunotherapy that harnesses the human immune system to fight cancer has received
widespread attention and become a mainstream strategy for cancer treatment. Cancer …
widespread attention and become a mainstream strategy for cancer treatment. Cancer …
Polymeric particle-based therapies for acute inflammatory diseases
ER Brannon, MV Guevara, NJ Pacifici, JK Lee… - Nature Reviews …, 2022 - nature.com
Acute inflammation is essential for initiating and coordinating the body's response to injuries
and infections. However, in acute inflammatory diseases, inflammation is not resolved but …
and infections. However, in acute inflammatory diseases, inflammation is not resolved but …
A nanomedicine fabricated from gold nanoparticles‐decorated metal–organic framework for cascade chemo/chemodynamic cancer therapy
Y Ding, H Xu, C Xu, Z Tong, S Zhang, Y Bai… - Advanced …, 2020 - Wiley Online Library
The incorporation of new modalities into chemotherapy greatly enhances the anticancer
efficacy combining the merits of each treatment, showing promising potentials in clinical …
efficacy combining the merits of each treatment, showing promising potentials in clinical …
Deep exploration of random forest model boosts the interpretability of machine learning studies of complicated immune responses and lung burden of nanoparticles
F Yu, C Wei, P Deng, T Peng, X Hu - Science advances, 2021 - science.org
The development of machine learning provides solutions for predicting the complicated
immune responses and pharmacokinetics of nanoparticles (NPs) in vivo. However, highly …
immune responses and pharmacokinetics of nanoparticles (NPs) in vivo. However, highly …
Safety challenges and application strategies for the use of dendrimers in medicine
X Li, A Naeem, S Xiao, L Hu, J Zhang, Q Zheng - Pharmaceutics, 2022 - mdpi.com
Dendrimers are used for a variety of applications in medicine but, due to their host–guest
and entrapment characteristics, are particularly used for the delivery of genes and drugs …
and entrapment characteristics, are particularly used for the delivery of genes and drugs …
A review on reactive oxygen species (ROS)-inducing nanoparticles activated by uni-or multi-modal dynamic treatment for oncotherapy
J Lin, D Li, C Li, Z Zhuang, C Chu, KK Ostrikov… - Nanoscale, 2023 - pubs.rsc.org
Cancer seriously threatens human health. As compared to normal tissue cells, tumor cells
are generally more susceptible to oxidative stress and accumulate higher concentrations of …
are generally more susceptible to oxidative stress and accumulate higher concentrations of …
A nanomedicine structure–activity framework for research, development, and regulation of future cancer therapies
Despite their clinical success in drug delivery applications, the potential of theranostic
nanomedicines is hampered by mechanistic uncertainty and a lack of science-informed …
nanomedicines is hampered by mechanistic uncertainty and a lack of science-informed …
Self-adjuvanting cancer nanovaccines
Nanovaccines, a new generation of vaccines that use nanoparticles as carriers and/or
adjuvants, have been widely used in the prevention and treatment of various diseases …
adjuvants, have been widely used in the prevention and treatment of various diseases …
[HTML][HTML] Intelligent nanogels with self-adaptive responsiveness for improved tumor drug delivery and augmented chemotherapy
For cancer nanomedicine, the main goal is to deliver therapeutic agents effectively to solid
tumors. Here, we report the unique design of self-adaptive ultrafast charge-reversible …
tumors. Here, we report the unique design of self-adaptive ultrafast charge-reversible …