Salivary gland function, development, and regeneration

AM Chibly, MH Aure, VN Patel… - Physiological …, 2022 - journals.physiology.org
Salivary glands produce and secrete saliva, which is essential for maintaining oral health
and overall health. Understanding both the unique structure and physiological function of …

[HTML][HTML] Radiation-induced salivary gland dysfunction: mechanisms, therapeutics and future directions

KJ Jasmer, KE Gilman, K Muñoz Forti… - Journal of clinical …, 2020 - mdpi.com
Salivary glands sustain collateral damage following radiotherapy (RT) to treat cancers of the
head and neck, leading to complications, including mucositis, xerostomia and …

Prevention and treatment of radiotherapy‐induced side effects

L Barazzuol, RP Coppes, P van Luijk - Molecular oncology, 2020 - Wiley Online Library
Radiotherapy remains a mainstay of cancer treatment, being used in roughly 50% of
patients. The precision with which the radiation dose can be delivered is rapidly improving …

Salivary gland hypofunction and xerostomia in head and neck radiation patients

SB Jensen, A Vissink, KH Limesand… - JNCI …, 2019 - academic.oup.com
Background The most manifest long-term consequences of radiation therapy in the head
and neck cancer patient are salivary gland hypofunction and a sensation of oral dryness …

[HTML][HTML] Neurodegenerative processes in Huntington's disease

D Bano, F Zanetti, Y Mende, P Nicotera - Cell death & disease, 2011 - nature.com
Huntington's disease (HD) is a complex and severe disorder characterized by the gradual
and the progressive loss of neurons, predominantly in the striatum, which leads to the typical …

[HTML][HTML] Hormesis, cell death and aging

I Martins, L Galluzzi, G Kroemer - Aging (Albany NY), 2011 - ncbi.nlm.nih.gov
Frequently, low doses of toxins and other stressors not only are harmless but also activate
an adaptive stress response that raise the resistance of the organism against high doses of …

[HTML][HTML] Regulation of the IGF1 signaling pathway is involved in idiopathic pulmonary fibrosis induced by alveolar epithelial cell senescence and core fucosylation

W Sun, X Jing, X Yang, H Huang, Q Luo, S Xia… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) mainly occurs in elderly people over the age of sixty. IPF
pathogenesis is associated with alveolar epithelial cells (AECs) senescence. Activation of …

A review of radiation countermeasures focusing on injury-specific medicinals and regulatory approval status: part III. Countermeasures under early stages of …

VK Singh, BK Hanlon, PT Santiago… - International journal of …, 2017 - Taylor & Francis
Purpose: Terrorist attacks, with their intent to maximize psychological and economic damage
as well as inflicting sickness and death on given targeted populations, are an ever-growing …

Regulation of spermatogenesis and reproductive capacity by Igf3 in tilapia

M Li, X Liu, S Dai, H Xiao, S Qi, Y Li, Q Zheng… - Cellular and Molecular …, 2020 - Springer
A novel insulin-like growth factor (igf3), which is exclusively expressed in the gonads, has
been widely identified in fish species. Recent studies have indicated that Igf3 regulates …

Radiotherapy-induced salivary dysfunction: Structural changes, pathogenetic mechanisms and therapies

MD Acauan, MAZ Figueiredo, K Cherubini… - Archives of Oral …, 2015 - Elsevier
Purpose This review addressed the structural changes observed in salivary glands and
pathogenic mechanisms resulting from oxidative stress caused by radiotherapy. The …