Ischemia/reperfusion injury following acute myocardial infarction: a critical issue for clinicians and forensic pathologists

M Neri, I Riezzo, N Pascale, C Pomara… - Mediators of …, 2017 - Wiley Online Library
Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality. Reperfusion
strategies are the current standard therapy for AMI. However, they may result in paradoxical …

[HTML][HTML] COVID-19-associated cardiovascular morbidity in older adults: a position paper from the Italian Society of Cardiovascular Researches

F Moccia, A Gerbino, V Lionetti, M Miragoli… - Geroscience, 2020 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells following
binding with the cell surface ACE2 receptors, thereby leading to coronavirus disease 2019 …

[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach… - Redox biology, 2017 - Elsevier
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

Free radicals and antioxidants–quo vadis?

B Halliwell - Trends in pharmacological sciences, 2011 - cell.com
The field of free radicals and antioxidants, or 'redox biology', is fundamental to aerobic life.
Aerobes constantly make reactive species, but modulate their actions by synthesizing …

Mitochondria as a source of reactive oxygen and nitrogen species: from molecular mechanisms to human health

TR Figueira, MH Barros, AA Camargo… - Antioxidants & redox …, 2013 - liebertpub.com
Mitochondrially generated reactive oxygen species are involved in a myriad of signaling and
damaging pathways in different tissues. In addition, mitochondria are an important target of …

[HTML][HTML] Protein oxidative modifications: beneficial roles in disease and health

Z Cai, LJ Yan - Journal of biochemical and pharmacological …, 2013 - ncbi.nlm.nih.gov
Protein oxidative modifications, also known as protein oxidation, are a major class of protein
posttranslational modifications. They are caused by reactions between protein amino acid …

Cardiac oxidative stress and inflammatory cytokines response after myocardial infarction

M Neri, V Fineschi, M Di Paolo… - Current vascular …, 2015 - ingentaconnect.com
Oxidative stress in heart failure or during ischemia/reperfusion occurs as a result of the
excessive generation or accumulation of free radicals or their oxidation products. Free …

Adverse cardiac remodelling after acute myocardial infarction: old and new biomarkers

AE Berezin, AA Berezin - Disease Markers, 2020 - Wiley Online Library
The prevalence of heart failure (HF) due to cardiac remodelling after acute myocardial
infarction (AMI) does not decrease regardless of implementation of new technologies …

[HTML][HTML] Ischemia/reperfusion injury and cardioprotective mechanisms: role of mitochondria and reactive oxygen species

MG Perrelli, P Pagliaro, C Penna - World journal of cardiology, 2011 - ncbi.nlm.nih.gov
Reperfusion therapy must be applied as soon as possible to attenuate the ischemic insult of
acute myocardial infarction (AMI). However reperfusion is responsible for additional …

Antineoplastic drug-induced cardiotoxicity: a redox perspective

G Varricchi, P Ameri, C Cadeddu, A Ghigo… - Frontiers in …, 2018 - frontiersin.org
Antineoplastic drugs can be associated with several side effects, including cardiovascular
toxicity (CTX). Biochemical studies have identified multiple mechanisms of CTX …