Obesity and heart failure with preserved ejection fraction (HFpEF) represent two
intermingling epidemics driving perhaps the greatest unmet health problem in …

The NIH has recently highlighted the importance of sexual dimorphisms and has mandated
inclusion of both sexes in clinical trials and basic research. In this review we highlight new …

Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …

Background Obesity is a major risk factor for cardiovascular disease, but the most predictive
measure for different ethnic populations is not clear. We aimed to assess whether markers of …

Glucocorticoids (GCs) have long been accepted as being catabolic in nature, liberating
energy substrates during times of stress to supply the increased metabolic demand of the …

During the last decades, research on adipose tissues has spread in parallel with the
extension of obesity. Several observations converged on the idea that adipose tissues are …

Insulin resistance occurs in obesity and Type II (non-insulin-dependent) diabetes mellitus,
but it is also a prominent feature of lipodystrophy. Adipose tissue could play a crucial part in …

The relative impacts of regional and generalized adiposity on insulin sensitivity have not
been fully defined. Therefore, we investigated the relationship of insulin sensitivity …

T HE ROLE of inherited and nongenetic factors in individual differences observed in the
level of sc fat on the trunk and abdominal areas and in the abdominal visceral deposit is …

Lipodystrophies have been recognized since at least the nineteenth century and, despite
their rarity, tended to attract considerable medical attention because of the severity and …