Automation in the life science research laboratory
I Holland, JA Davies - Frontiers in bioengineering and biotechnology, 2020 - frontiersin.org
Protocols in the academic life science laboratory are heavily reliant on the manual
manipulation of tools, reagents and instruments by a host of research staff and students. In …
manipulation of tools, reagents and instruments by a host of research staff and students. In …
The bioeconomy, the challenge of the century for policy makers
J Philp - New biotechnology, 2018 - Elsevier
Abstract During the Industrial Revolution, it became clear that wood was unsuited as an
energy source for industrial production, especially iron smelting. However, the transition to …
energy source for industrial production, especially iron smelting. However, the transition to …
Harnessing the potential of machine learning for advancing “quality by design” in biomanufacturing
Ensuring consistent high yields and product quality are key challenges in biomanufacturing.
Even minor deviations in critical process parameters (CPPs) such as media and feed …
Even minor deviations in critical process parameters (CPPs) such as media and feed …
When is an in silico representation a digital twin? A biopharmaceutical industry approach to the digital twin concept
Digital twins (DTs) are expected to render process development and life-cycle management
much more cost-effective and time-efficient. A DT definition, a brief retrospect on their history …
much more cost-effective and time-efficient. A DT definition, a brief retrospect on their history …
Bioinformatics for the synthetic biology of natural products: integrating across the Design–Build–Test cycle
Covering: 2000 to 2016 Progress in synthetic biology is enabled by powerful bioinformatics
tools allowing the integration of the design, build and test stages of the biological …
tools allowing the integration of the design, build and test stages of the biological …
A transatlantic perspective on 20 emerging issues in biological engineering
Advances in biological engineering are likely to have substantial impacts on global society.
To explore these potential impacts we ran a horizon scanning exercise to capture a range of …
To explore these potential impacts we ran a horizon scanning exercise to capture a range of …
Sequential multivariate cell culture modeling at multiple scales supports systematic shaping of a monoclonal antibody toward a quality target
The development of cell culture processes is highly complex and requires a large number of
experiments on various scales to define the design space of the final process and fulfil the …
experiments on various scales to define the design space of the final process and fulfil the …
Puddle: A dynamic, error-correcting, full-stack microfluidics platform
M Willsey, AP Stephenson, C Takahashi… - Proceedings of the …, 2019 - dl.acm.org
Microfluidic devices promise to automate wetlab procedures by manipulating small chemical
or biological samples. This technology comes in many varieties, all of which aim to save …
or biological samples. This technology comes in many varieties, all of which aim to save …
[HTML][HTML] OpenWorkstation: A modular open-source technology for automated in vitro workflows
Automation liberates scientific staff from repetitive tasks, decreases the probability of human
error and consequently enhances the reproducibility of lab experiments. However, the use of …
error and consequently enhances the reproducibility of lab experiments. However, the use of …
LLMs can generate robotic scripts from goal-oriented instructions in biological laboratory automation
The use of laboratory automation by all researchers may substantially accelerate scientific
activities by humans, including those in the life sciences. However, computer programs to …
activities by humans, including those in the life sciences. However, computer programs to …