Events during ischemia/reperfusion (I/R) injury include: neutrophil‐mediated endothelial
cytotoxicity and activation, generation of free radicals, triggering of cytokines and …

The rapid restoration of coronary flow to the jeopardized myocardium has become an
essential part of therapy after acute myocardial infarction. Despite an open infarct-related …

Background Recent studies demonstrated that the “no reflow” phenomenon after coronary
reflow implies the presence of advanced myocardial damage. In this study, we verified the …

Objectives: We investigated the association between hyperglycemia and the no-reflow
phenomenon in patients with acute myocardial infarction (AMI). Background: Hyperglycemia …

OBJECTIVES We assessed whether the intravenous administration of nicorandil, an
adenosine triphosphate (ATP)-sensitive K+ channel opener, exerts beneficial effect on …

Background Epicardial coronary flow is occasionally reduced even after coronary
intervention despite the absence of vessel obstruction in patients with acute myocardial …

Both animal models of experimental myocardial infarction and clinical studies on reperfusion
therapy for acute myocardial infarction have provided evidence of impaired tissue perfusion …

BACKGROUND Patency of the infarct-related artery (IRA) after acute myocardial infarction
(AMI) may not reflect the magnitude of tissue perfusion. In animal models of AMI, myocardial …

Background Experimental and clinical evidence indicates that myocardial ischemia often
damages the coronary microvasculature (“no-reflow” phenomenon). In this study, we …

Background—This study investigated whether the extent of perfusion defect determined by
intravenous myocardial contrast echocardiography (MCE) in patients with acute myocardial …