Metal–organic frameworks and their composites for chronic wound healing: from bench to bedside

Y Xiong, Q Feng, L Lu, X Qiu, S Knoedler… - Advanced …, 2024 - Wiley Online Library
Chronic wounds are characterized by delayed and dysregulated healing processes. As
such, they have emerged as an increasingly significant threat. The associated morbidity and …

Nanozymes for regenerative medicine

X Mou, Q Wu, Z Zhang, Y Liu, J Zhang, C Zhang… - Small …, 2022 - Wiley Online Library
Nanozymes refer to nanomaterials that catalyze enzyme substrates into products under
relevant physiological conditions following enzyme kinetics. Compared to natural enzymes …

[HTML][HTML] Ultrasmall Fe-doped carbon dots nanozymes for photoenhanced antibacterial therapy and wound healing

Y Liu, B Xu, M Lu, S Li, J Guo, F Chen, X Xiong, Z Yin… - Bioactive materials, 2022 - Elsevier
Pathogenic bacteria pose a devastating threat to public health. However, because of the
growing bacterial antibiotic resistance, there is an urgent need to develop alternative …

A library of ROS‐catalytic metalloenzyme mimics with atomic metal centers

S Cao, Z Zhao, Y Zheng, Z Wu, T Ma, B Zhu… - Advanced …, 2022 - Wiley Online Library
Metal N‐coordinated centers supported by carbonaceous substrates have emerged as
promising artificial metalloenzymes (AMEs) to mimic the biocatalytic effects of their natural …

Photodynamic alginate Zn-MOF thermosensitive hydrogel for accelerated healing of infected wounds

W Zhang, B Wang, G Xiang, T Jiang… - ACS Applied Materials & …, 2023 - ACS Publications
Antibiotic resistance reduces the effectiveness of infected wound healing, and it is necessary
to develop a new strategy to promote infected wound healing without using antibiotics. Here …

Reactive oxygen nanobiocatalysts: activity-mechanism disclosures, catalytic center evolutions, and changing states

S Cao, Y Long, S Xiao, Y Deng, L Ma, M Adeli… - Chemical Society …, 2023 - pubs.rsc.org
Benefiting from low costs, structural diversities, tunable catalytic activities, feasible
modifications, and high stability compared to the natural enzymes, reactive oxygen …

Pd‐single‐atom coordinated biocatalysts for chem‐/sono‐/photo‐trimodal tumor therapies

F Du, L Liu, Z Wu, Z Zhao, W Geng, B Zhu… - Advanced …, 2021 - Wiley Online Library
The diversity, complexity, and heterogeneity of malignant tumor seriously undermine the
efficiency of mono‐modal treatment. Recently, multi‐modal therapeutics with enhanced …

ROS‐catalytic transition‐metal‐based enzymatic nanoagents for tumor and bacterial eradication

L Li, L Cao, X Xiang, X Wu, L Ma… - Advanced Functional …, 2022 - Wiley Online Library
The extensive research into developing new nanomedicines during the past few years has
witnessed significant progress in diverse biomedical fields, especially for combating drug …

Biocatalytic and antioxidant nanostructures for ROS scavenging and biotherapeutics

L Wang, B Zhu, Y Deng, T Li, Q Tian… - Advanced Functional …, 2021 - Wiley Online Library
In human systems, reactive oxygen species (ROS) significantly affect different physiological
activities and play critical roles in diverse living processes. It is widely known that excessive …

Modulating Electron Transfer in Vanadium‐Based Artificial Enzymes for Enhanced ROS‐Catalysis and Disinfection

L Li, S Cao, Z Wu, R Guo, L Xie, L Wang… - Advanced …, 2022 - Wiley Online Library
Nanomaterials‐based artificial enzymes (AEs) have flourished for more than a decade.
However, it is still challenging to further enhance their biocatalytic performances due to the …