Hyperglycemia, a neglected factor during cancer progression

W Duan, X Shen, J Lei, Q Xu, Y Yu, R Li… - BioMed research …, 2014 - Wiley Online Library
Recent evidence from large cohort studies suggests that there exists a higher cancer
incidence in people with type 2 diabetes (DM2). However, to date, the potential reasons for …

Gemcitabine chemoresistance in pancreatic cancer: molecular mechanisms and potential solutions

R Andersson, U Aho, BI Nilsson, GJ Peters… - Scandinavian journal …, 2009 - Taylor & Francis
Ductal pancreatic adenocarcinoma is associated with a very poor prognosis and most
patients are given palliative care. Chemotherapy in the form of gemcitabine has been found …

Validation of C-reactive protein levels as a prognostic indicator for survival in a large cohort of pancreatic cancer patients

J Szkandera, M Stotz, G Absenger, T Stojakovic… - British journal of …, 2014 - nature.com
Background: Recent evidence indicates that the host inflammatory response has an
important role in the tumour progression. Elevated C-reactive protein (CRP) levels have …

Preoperative neutrophil‐to‐lymphocyte ratio (NLR) is associated with reduced disease‐free survival following curative resection of pancreatic adenocarcinoma

G Garcea, N Ladwa, CP Neal… - World journal of …, 2011 - Wiley Online Library
Background Serological proinflammatory markers such as C‐reactive protein (CRP),
neutrophil‐to‐lymphocyte ratio (NLR), and platelet‐to‐lymphocyte ratio (PLR) have been …

Chronic inflammation and pancreatic cancer

CJ McKay, P Glen, DC McMillan - Best practice & research Clinical …, 2008 - Elsevier
There is a proven association between carcinoma of the pancreas and both the sporadic
and hereditary forms of chronic pancreatitis. In chronic pancreatitis the standardised …

Diagnostic usefulness of serum interleukin 6 (IL‐6) and C‐reactive protein (CRP) in the differentiation between pancreatic cancer and chronic pancreatitis

B Mroczko, M Groblewska, M Gryko… - Journal of clinical …, 2010 - Wiley Online Library
Previous studies have shown elevated serum levels of interleukin 6 (IL‐6) and C‐reactive
protein (CRP) in patients with pancreatic cancer (PC). The aim of this study was to assess …

Detection of pancreatic cancer using antibody microarray‐based serum protein profiling

J Ingvarsson, C Wingren, A Carlsson, P Ellmark… - …, 2008 - Wiley Online Library
The driving force behind oncoproteomics is to identify protein signatures that are associated
with a particular malignancy. Here, we have used a recombinant scFv antibody microarray in …

Protein deep sequencing applied to biobank samples from patients with pancreatic cancer

D Ansari, R Andersson, MP Bauden… - Journal of cancer …, 2015 - Springer
Purpose Pancreatic cancer is commonly detected at advanced stages when the tumor is no
longer amenable to surgical resection. Therefore, finding biomarkers for early stage disease …

Plasma inflammatory cytokines and survival of pancreatic cancer patients

A Babic, N Schnure, NP Neupane… - Clinical and …, 2018 - journals.lww.com
Objectives: Inflammation and inflammatory conditions have been associated with pancreatic
cancer risk and progression in a number of clinical, epidemiological, and animal model …

Impact of anastomotic complications on outcome after laparoscopic gastrectomy for early gastric cancer

Y Nagasako, S Satoh, J Isogaki, K Inaba… - Journal of British …, 2012 - academic.oup.com
Background The effects of anastomotic complications after laparoscopically assisted
gastrectomy (LAG) have not been studied widely. The aims of this observational study were …