[HTML][HTML] Re-evaluation of the linear no-threshold (LNT) model using new paradigms and modern molecular studies
S Tharmalingam, S Sreetharan, AL Brooks… - Chemico-Biological …, 2019 - Elsevier
The linear no-threshold (LNT) model is currently used to estimate low dose radiation (LDR)
induced health risks. This model lacks safety thresholds and postulates that health risks …
induced health risks. This model lacks safety thresholds and postulates that health risks …
Exposure to low dose ionising radiation: molecular and clinical consequences
LM Martin, B Marples, TH Lynch, D Hollywood… - Cancer letters, 2013 - Elsevier
This review article provides a comprehensive overview of the experimental data detailing
the incidence, mechanism and significance of low dose hyper-radiosensitivity (HRS) …
the incidence, mechanism and significance of low dose hyper-radiosensitivity (HRS) …
Gamma histone 2AX (γ-H2AX) as a predictive tool in radiation oncology
S Pouliliou, MI Koukourakis - Biomarkers, 2014 - Taylor & Francis
Ionizing radiation cause DNA damage to cells, leading them to cell death via DNA double-
strand breaks (DSBs) formation. DSBs formation is followed immediately by histone H2AX …
strand breaks (DSBs) formation. DSBs formation is followed immediately by histone H2AX …
Potential risks associated with the use of ionizing radiation for imaging and treatment of colorectal cancer in Lynch syndrome patients
M Sun, J Moquet, M Ellender, S Bouffler, C Badie… - Familial Cancer, 2023 - Springer
The aim of this review is to investigate the literature pertaining to the potential risks of low-
dose ionizing radiation to Lynch syndrome patients by use of computed tomography (CT) …
dose ionizing radiation to Lynch syndrome patients by use of computed tomography (CT) …
Moving the Needle Forward in Genomically-Guided Precision Radiation Treatment
A Tam, BD Mercier, RM Thomas, E Tizpa, IG Wong… - Cancers, 2023 - mdpi.com
Simple Summary Genetic information is seldom incorporated in formulating radiation
treatment recommendations for patients with cancer, even though genetic information is now …
treatment recommendations for patients with cancer, even though genetic information is now …
Multiple-integrations of HPV16 genome and altered transcription of viral oncogenes and cellular genes are associated with the development of cervical cancer
X Lu, Q Lin, M Lin, P Duan, L Ye, J Chen, X Chen… - PLoS …, 2014 - journals.plos.org
The constitutive expression of the high-risk HPV E6 and E7 viral oncogenes is the major
cause of cervical cancer. To comprehensively explore the composition of HPV16 early …
cause of cervical cancer. To comprehensively explore the composition of HPV16 early …
Investigations of electrical properties of structures Al-DNA-ITO-Al exposed to alpha particles
HMJ Al-Ta'ii, YM Amin, V Periasamy - Radiation Measurements, 2015 - Elsevier
The detection of alpha particles and other radiation sources has been an important field of
research since the inception of radioactive materials in medical technology approximately a …
research since the inception of radioactive materials in medical technology approximately a …
Low-dose hyper-radiosensitivity is not a common effect in normal asynchronous and G2-phase fibroblasts of cancer patients
D Słonina, B Biesaga, A Janecka, D Kabat… - International Journal of …, 2014 - Elsevier
Purpose In our previous study, using the micronucleus assay, a low-dose hyper-
radiosensitivity (HRS)-like phenomenon was observed for normal fibroblasts of 2 of the 40 …
radiosensitivity (HRS)-like phenomenon was observed for normal fibroblasts of 2 of the 40 …
Autophagy influences the low-dose hyper-radiosensitivity of human lung adenocarcinoma cells by regulating MLH1
Q Wang, Z Xiao, Z Lin, J Zhou, W Chen… - … Journal of Radiation …, 2017 - Taylor & Francis
Purpose: To investigate the impact of autophagy on the low-dose hyper-radiosensitivity
(HRS) of human lung adenocarcinoma cells via MLH1 regulation. Materials and methods …
(HRS) of human lung adenocarcinoma cells via MLH1 regulation. Materials and methods …
An association between low-dose hyper-radiosensitivity and the early G2-phase checkpoint in normal fibroblasts of cancer patients
D Słonina, A Gasińska, B Biesaga, A Janecka, D Kabat - DNA repair, 2016 - Elsevier
In our previous study, low-dose hyper-radiosensitivity (HRS) effect was demonstrated for
normal fibroblasts (asynchronous and G2-phase enriched) of 4 of the 25 cancer patients …
normal fibroblasts (asynchronous and G2-phase enriched) of 4 of the 25 cancer patients …