This “Year in review” presents a selection of research themes and individual studies from the
clinical osteoarthritis (OA) field (epidemiology and therapy) and includes noteworthy …

Objective To evaluate the global burden of musculoskeletal (MSK) disorders, as well as the
five common conditions, and their relevant risk factors from 1990 to 2019. Design Data from …

Background Spinal cord injuries, often resulting from spine fractures, can lead to severe
lifelong symptoms such as paraplegia and even mortality. Over the past few decades, there …

Osteoarthritis (OA) is a complex condition that involves both apoptosis and senescence and
currently cannot be cured. Fibroblast growth factor 21 (FGF21), known for its role as a potent …

The complex, gradient physiological structure of articular cartilage is a severe hindrance of
its self‐repair, leaving the clinical treatment of cartilage defects a demanding issue to be …

Importance The degree to which health and economic outcomes of musculoskeletal
disorders are attributable to high body mass index (BMI) has not been quantified on a global …

Introduction Intervertebral disc degeneration (IVDD) is an important contributor of low back
pain, which represents one of the most disabling symptoms within the adult population …

Intervertebral disc degeneration (IVDD) is a major cause of low back pain. Diabetes mellitus
is a chronic inflammatory disease that may cause or aggravate IVDD; however, the …

Purpose We aimed to estimate the incidence, prevalence and years lived with disability
(YLDs) of spinal cord injury (SCI) in China in 2019 and temporal trends from 1990 to 2019 …

This study explores the prevalence and correlates of bone and joint diseases and its
association with falls among older adults in India. Data from the Longitudinal Aging Study in …