Aging is a major risk factor for numerous chronic diseases. Vaccination offers a promising
strategy to combat these age-related diseases by targeting specific antigens and inducing …

Building on the classification of the clinical phenotype and prediction of clinical trajectory
based on individual patients' autoantigen and/or autoantibody profile, cellular therapies …

The pathogenesis of pulmonary fibrosis, including idiopathic pulmonary fibrosis (IPF) and
other forms of interstitial lung disease, involves a complex interplay of various factors …

Fibrosis is commonly associated with chronic rheumatic diseases, and causes substantial
morbidity and mortality. Treatment of fibrosis is extremely challenging but is badly needed …

Abstract Background & Aims Liver fibrosis and cirrhosis resulting from chronic liver injury are
major health burdens worldwide. However, clinical interventions and therapies that target …

Human diseases are characterized by intricate cellular dynamics. Single-cell sequencing
provides critical insights, yet a persistent gap remains in computational tools for detailed …

Fibrosis, the pathological end stage of chronic inflammatory diseases, results from
extracellular matrix deposition by fibrogenic fibroblasts. In this issue of Cell Stem Cell …

Background Animal models are essential to understand the physiopathology of human
diseases but also to evaluate new therapies. However, for several diseases there is no …

At present, surgical resection is the most effective method for the treatment of gastric cancer.
However, death caused by inoperable metastasis is still very common, despite research in …

Idiopathic pulmonary fibrosis (IPF) is an aggressive interstitial lung disease associated with
progressive and irreversible deterioration of respiratory functions that lacks curative …